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The ileocecal sphincter at the junction of the small intestine (ileum) and the large intestine, which functions to limit the reflux of colonic contents back into the ileum. The sphincter of Oddi , or Glisson's sphincter, controlling secretions from the liver , pancreas and gall bladder into the duodenum .
In the human digestive system, a bolus (a small rounded mass of chewed up food) enters the stomach through the esophagus via the lower esophageal sphincter. The stomach releases proteases (protein-digesting enzymes such as pepsin ), and hydrochloric acid , which kills or inhibits bacteria and provides the acidic pH of 2 for the proteases to work.
The angle of His forms an anatomical sphincter. This prevents the reflux of stomach acid , digestive enzymes , and duodenal bile from entering the esophagus. [ 4 ] [ 5 ] This is important in preventing gastroesophageal reflux disease and inflammation of the esophagus.
The human digestive system consists of the gastrointestinal tract plus the accessory organs of digestion (the tongue, salivary glands, pancreas, liver, and gallbladder). Digestion involves the breakdown of food into smaller and smaller components, until they can be absorbed and assimilated into the body.
Starting from the cardiac orifice it begins at the cardiac notch, forming an arch backward, upward, and to the left. A horizontal plane across from the cardiac notch encloses an area called the fundus of the stomach. The highest point of the fundic convex is on a level with the sixth left costal cartilage.
Upper and lower human gastrointestinal tract. The esophagus (American English), oesophagus (British English), or œsophagus (archaic spelling) (see spelling difference) all / iː ˈ s ɒ f ə ɡ ə s, ɪ-/; [1] pl.: ((o)e)(œ)sophagi or ((o)e)(œ)sophaguses), colloquially known also as the food pipe, food tube, or gullet, is an organ in vertebrates through which food passes, aided by ...
The digestive system has a complex system of motility and secretion regulation which is vital for proper function. This task is accomplished via a system of long reflexes from the central nervous system (CNS), short reflexes from the enteric nervous system (ENS) and reflexes from GI peptides working in harmony with each other. [4]
In the digestive system, VIP seems to induce smooth muscle relaxation (lower esophageal sphincter, stomach, gallbladder), stimulate secretion of water into pancreatic juice and bile, and cause inhibition of gastric acid secretion and absorption from the intestinal lumen. [11]