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[4] [5] This phenomenon of poison shyness is the rationale for poisons that kill only after multiple doses. Besides being directly toxic to the mammals that ingest them, including dogs, cats, and humans, many rodenticides present a secondary poisoning risk to animals that hunt or scavenge the dead corpses of rats. [6]
Tetramethylenedisulfotetramine (TETS) is an organic compound used as a rodenticide (rat poison). [2] It is an odorless, tasteless white powder that is slightly soluble in water, DMSO and acetone, and insoluble in methanol and ethanol. It is a sulfamide derivative. It can be synthesized by reacting sulfamide with formaldehyde solution in ...
Next Richter set out to test the compound on a large scale. He determined rats will not cross streets and therefore city blocks were used as test areas. Local Boy Scouts volunteered to distribute the poison. When the first tests returned large amounts of dead rats, the tests were extended to a 200-block area with poor housing.
The primary antidote to brodifacoum poisoning is immediate administration of vitamin K 1 (dosage for humans: initially slow intravenous injections of 10–25 mg repeated at 3–6 hours until normalisation of the prothrombin time; then 10 mg orally four times daily as a "maintenance dose"). It is an extremely effective antidote, provided the ...
The law will place a permanent moratorium on a rat poison that unintentionally also kills predators, such as mountain lions, coyotes and other animals.
The median infective dose (ID 50) is the number of organisms received by a person or test animal qualified by the route of administration (e.g., 1,200 org/man per oral). Because of the difficulties in counting actual organisms in a dose, infective doses may be expressed in terms of biological assay, such as the number of LD 50 s to some test ...