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Calcium carbonate is the type of calcium supplement that’s most likely to cause constipation, Dr. Uradomo says. But the research on calcium and constipation is mixed, Bragagnini says.
Hypocalcemia is a medical condition characterized by low calcium levels in the blood serum. [5] The normal range of blood calcium is typically between 2.1–2.6 mmol/L (8.8–10.7 mg/dL, 4.3–5.2 mEq/L), while levels less than 2.1 mmol/L are defined as hypocalcemic.
In a healthy physiology, extracellular calcium levels are maintained within a tight range through the actions of parathyroid hormone, vitamin D and the calcium sensing receptor. [1] Disorders in calcium metabolism can lead to hypocalcemia, decreased plasma levels of calcium or hypercalcemia, elevated plasma calcium levels.
[17] [27] Certain calcium channel blockers such as nifedipine and verapamil can cause severe constipation due to dysfunction of motility in the rectosigmoid colon. [28] Supplements such as calcium and iron supplements can also have constipation as a notable side effect. [29] [30]
Over 40% of Americans do not consume enough calcium, which puts them at an increased risk of osteoporosis, bone fractures, and heart problems.
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