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  2. CADASIL - Wikipedia

    en.wikipedia.org/wiki/CADASIL

    CADASIL or CADASIL syndrome, involving cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, is the most common form of hereditary stroke disorder and is thought to be caused by mutations of the NOTCH3 gene on chromosome 19. [1] The disease belongs to a family of disorders called the leukodystrophies.

  3. CARASIL - Wikipedia

    en.wikipedia.org/wiki/CARASIL

    CARASIL is an autosomal recessive disease, meaning that both parents must be a carrier for the allele in order for the disease to be passed on to the child. [11] As with other autosomal recessive diseases, the likelihood of receiving a recessive allele from both parents increases if the parents are closely related to each other ( consanguineous ).

  4. Leukoencephalopathy with vanishing white matter - Wikipedia

    en.wikipedia.org/wiki/Leukoencephalopathy_with...

    Leukoencephalopathy with vanishing white matter (VWM disease) is an autosomal recessive neurological disease. The cause of the disease are mutations in any of the 5 genes encoding subunits of the translation initiation factor eIF2B: EIF2B1, EIF2B2, EIF2B3, EIF2B4, or EIF2B5. The disease belongs to a family of conditions called the Leukodystrophies.

  5. Cerebrovascular disease - Wikipedia

    en.wikipedia.org/wiki/Cerebrovascular_disease

    Congenital diseases are medical conditions that are present at birth that may be associated with or inherited through genes. [16] Examples of congenital cerebrovascular diseases include arteriovenous malformations, germinal matrix hemorrhage, and CADASIL (cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy). [9]

  6. NOTCH3 - Wikipedia

    en.wikipedia.org/wiki/NOTCH3

    Micrograph showing CADASIL with a Notch 3 immunostain. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy . [6] Mutations in NOTCH3 have also been identified in families with Alzheimer's disease. [7]

  7. Lyme disease signs and symptoms: When should you seek ... - AOL

    www.aol.com/article/lifestyle/2018/05/25/lyme...

    Lyme disease is caused by infected black-legged (or deer) ticks and symptoms of the disease may vary, depending on how long it takes to discover the signs. Show comments Advertisement

  8. What Is Non-Alcoholic Fatty Liver Disease—Plus 5 Sneaky Signs ...

    www.aol.com/non-alcoholic-fatty-liver-disease...

    Nonalcoholic fatty liver disease is a common but often overlooked condition affecting 1 in 4 Americans. It results from fat buildup in the liver, which can lead to inflammation, scarring, and ...

  9. Great Danes Fool Themselves Into Thinking Mom Left Them Home ...

    www.aol.com/great-danes-fool-themselves-thinking...

    Dogs can really freak out when they think they're being left by their humans. It's called separation anxiety and can lead to a whole host of behavioral problems like barking, bathroom accidents ...