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It has several functions, such as the relaying of sensory and motor signals to the cerebral cortex [1] [2] and the regulation of consciousness, sleep, and alertness. [3] [4] Anatomically, it is a paramedian symmetrical structure of two halves (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain.
In neuroanatomy, the lateral geniculate nucleus (LGN; also called the lateral geniculate body or lateral geniculate complex) is a structure in the thalamus and a key component of the mammalian visual pathway. It is a small, ovoid, ventral projection of the thalamus where the thalamus connects with the optic nerve. There are two LGNs, one on the ...
The connections of the medial dorsal nucleus have even been used to delineate the prefrontal cortex of the Göttingen minipig brain. [ 7 ] By stereology the number of brain cells in the region has been estimated at around 6.43 million neurons in the adult human brain and 36.3 million glial cells , with the newborn having quite different numbers ...
Its function is modulatory on signals going through the thalamus (and the reticular nucleus). The thalamic reticular nucleus receives massive projections from the external segment of the globus pallidus , thought to play a part in disinhibition of thalamic cells, which is essential for initiation of movement (Parent and Hazrati, 1995).
Thalamic nuclei: (left thalamus, left view) MNG = Midline nuclear group AN = Anterior nuclear group MD = Medial dorsal nucleus VNG = Ventral nuclear group VA = Ventral anterior nucleus VL = Ventral lateral nucleus VPL = Ventral posterolateral nucleus VPM = Ventral posteromedial nucleus LNG = Lateral nuclear group PUL = Pulvinar MTh = Metathalamus
The first-order neurons from the trigeminal ganglion enter the pons and synapse in the principal (chief sensory) nucleus or spinal trigeminal nucleus.Axons of the second-order neurons cross the midline and terminate in the ventral posteromedial nucleus of the contralateral thalamus (as opposed to the ventral posterolateral nucleus, as in the dorsal column medial lemniscus (DCML) system).
The striatum is organized on a rostro-caudal axis, with the rostral putamen and caudate serving associative and cognitive functions and the caudal areas serving sensorimotor function. [6] Sometimes when the striatum is the expressed target the loop is referred to as the cortico-striatal-thalamic-cortical loop. [7]
In the human brain, the central lateral nucleus is a part of the anterior intralaminar nucleus in the thalamus. [1]: 2 The intralaminar nuclei project to many different regions of the brain, [2] The thalamus acts generally as a relay point for the brain for other areas of the brain to link to. The central lateral nucleus acts in a vital role in ...