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During pregnancy, increased uterine motility has led to decreased heart rate, cardiac arrhythmia, seizures, brain damage, and death in the fetus or neonate. [14] Use is linked to an increased risk of postpartum depression in the mother. [23] Certain learning and memory functions are impaired by centrally administered oxytocin. [24]
Similar to oxytocin, analogues bind to oxytocin receptors found along the muscles of the uterus and act as an agonist. During pregnancy, the number of oxytocin receptors increase until reaching their peak near completion of the pregnancy. An important note is that not all analogs of oxytocin work as an receptor agonist or as a uterotonic.
Oxytocin/ergometrine (trade name Syntometrine) is an obstetric combination drug. The components are synthetically produced oxytocin , a human hormone produced in the hypothalamus , and ergometrine , an alpha-adrenergic , dopaminergic and serotonin (5-HT 2 ) receptor agonist.
A high dose of oxytocin does not seem to have greater benefits than a standard dose. [9] There are risks associated with IV oxytocin induced labor. Risks include the women having induced contractions that are too vigorous, too close together (frequent), or that last too long, which may lead to added stress on the baby (changes in baby's heart ...
Side effects may also include ... mothers had been either injecting or orally taking oxycodone during pregnancy. [54] ... "oxybutynin", "oxytocin", or ...
Fever is also a common side effect with use of prostaglandin E 2. Administration of prostaglandin E 2 should be stopped if a person experiences side effects such as fever. [4] The insert and gel forms have been shown to have minimal gastrointestinal effects, but are more associated with increase stimulation of the uterus as well as fetal ...
During pregnancy, a baby is surrounded ... Oxytocin is further released during labour when the fetus stimulates the cervix and vagina, ... Side effects appear later ...
Oxytocin is produced in the brain and several reproductive tissues during pregnancy, while the receptors are produced in reproductive tissues. [35] During human parturition, the quantifiable level of blood plasma oxytocin rises: it becomes twice as much during the initial phase of dilation and continues to increase until the second stage of ...