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6% (< 60 years old), 20% (> 60 years old) [ 4 ] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [ 5 ] Symptoms can vary from none to severe. [ 1 ] Mild deficiency may have few or absent symptoms. [ 1 ]
[6] [14] [25] Vitamin B 12 deficiency can also cause symptoms of mania and psychosis. [26] [27] Among other problems, weakened immunity, reduced fertility and interruption of blood circulation in women may occur. [28] The main type of vitamin B12 deficiency anemia is pernicious anemia, [29] characterized by a triad of symptoms:
The Schilling test distinguished PA from other forms of B 12 deficiency, [50] specifically, from Imerslund–Gräsbeck syndrome, a B 12-deficiency caused by mutations in CUBN that codes for cubilin the cobalamin receptor. [1] Vitamin B12 deficiency is also prevalent in patients having Crohn's disease (CD) so it should be differentiated. [62]
The Good Housekeeping Institute tested more than 30 brands of B12 supplements, and chose Nature made B12 1000mcg as the best overall option, and Garden of Life Vitamin Code Raw B12 as the best ...
Vitamin B12 deficiency causes symptoms like fatigue, ... and treatment options. Vitamin B12 deficiency symptoms. ... it does represent 20% to 50% of the causes of vitamin B12 deficiency in adults.
Megaloblastic anemia, the most common cause of macrocytic anemia, is due to a deficiency of either vitamin B 12, folic acid, or both. [77] Deficiency in folate or vitamin B 12 can be due either to inadequate intake or insufficient absorption. Folate deficiency normally does not produce neurological symptoms, while B 12 deficiency does.