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William Canfield is a glycobiologist, chief scientific officer and founder of an Oklahoma City-based biotechnology company, Novazyme, which was acquired by Genzyme in August 2001 and developed, among other things, an enzyme that can stabilize (but not cure) Pompe disease, based on Canfield's ongoing research since 1998.
Genzyme claims that Dr. Robert Stonehill's character is based upon scientist and researcher William Canfield, [10] who founded Novazyme. [11] According to Roger Ebert's review, the character is based on Yuan-Tsong Chen , [ 6 ] a scientist and researcher from Duke University [ 12 ] who collaborated with Genzyme in producing Myozyme , the drug ...
Directed by Tom Vaughan, Extraordinary Measures stars Brendan Fraser as John Crowley and Keri Russell as Aileen Crowley, and also executive producer Harrison Ford as "Dr. Robert Stonehill" who is a composite character based primarily on Dr. William Canfield and inspired as well by other doctors Crowley worked with. [37]
Dr. Robert Lufkin says he taught lies in medical school about weight loss, diet, high blood pressure, and statins to prevent heart disease. Experts respond.
The FDA has placed a clinical hold on Astellas Pharma Inc's (OTC: ALPMY) FORTIS Phase 1/2 trial following a serious adverse event (SAE) of peripheral sensory neuropathy in one of the trial ...
Glycogen storage disease type II (GSD-II), also called Pompe disease, and formerly known as GSD-IIa or Limb–girdle muscular dystrophy 2V, is an autosomal recessive metabolic disorder [1] which damages muscle and nerve cells throughout the body.
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The volume of distribution of avalglucosidase alfa was 3.4 L in patients who had Pompe disease of a late onset. [12] The average half-life of avalglucosidase alfa was 1.6 hours, measured in patients with late stage Pompe disease. [12] There is little information available on the metabolism of the avalglucosidase alfa.