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Uterine fibroids, also known as uterine leiomyomas, fibromyoma or fibroids, are benign smooth muscle tumors of the uterus, part of the female reproductive system. [1] Most people [note 1] with fibroids have no symptoms while others may have painful or heavy periods. [1] If large enough, they may push on the bladder, causing a frequent need to ...
Leiomyoma enucleated from a uterus. External surface on left; cut surface on right. Micrograph of a small, well-circumscribed colonic leiomyoma arising from the muscularis mucosae and showing fascicles of spindle cells with eosinophilic cytoplasm and elongated, cigar-shaped nuclei Immunohistochemistry for β-catenin in uterine leiomyoma, which is negative as there is only staining of cytoplasm ...
Symptoms of uterine sarcoma include unusual vaginal bleeding or a mass in the vagina. [ 2 ] Risk factors for endometrial cancer include obesity , metabolic syndrome , type 2 diabetes , taking pills that contain estrogen without progesterone , a history of tamoxifen use, late menopause , and a family history of the condition.
Uterine serous carcinoma is a malignant form of serous tumor that originates in the uterus. It is an uncommon form of endometrial cancer that typically arises in postmenopausal women. It is typically diagnosed on endometrial biopsy , prompted by post-menopausal bleeding .
When the endometrial mucous membrane is found outside of the uterus in places such as the ovaries, it causes chronic pelvic pain with intercourse and menstrual cycles. Endometriomas can produce a toxic environment by producing estrogen, cytokines, interleukins, and other inflammatory substances, that could damage healthy endometriomal tissue.
[1] [a] A neoplasm is an abnormal growth of tissue that usually forms a tissue mass. [2] [3] [4] Vaginal neoplasms may be solid, cystic or of mixed type. [5] Vaginal cancers arise from vaginal tissue, with vaginal sarcomas develop from bone, cartilage, fat, muscle, blood vessels or other connective or supportive tissue.
Additionally, hematometra may develop as a complication of uterine or cervical surgery such as endometrial ablation, where scar tissue in the endometrium can "wall off" sections of endometrial glands and stroma causing blood to accumulate in the uterine cavity. [1] It can also develop after abortion, [4] as well as after childbirth.
Uterine sarcomas account for 3 to 9% of uterine cancers, and 5.5 to 9% of uterine sarcomas are adenosarcomas. [6] The most common presenting symptom is abnormal vaginal bleeding. Other symptoms include pelvic pain, abdominal mass, or vaginal discharge. [13] Uterine adenosarcoma commonly arise from the endometrium. [1]