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Some women with autoimmune diseases may have problems getting pregnant. This can happen for many reasons such as medication types or even disease types. [59] Tests can tell if fertility problems are caused by an autoimmune disease or an unrelated reason. Fertility treatments are able to help some women with autoimmune disease become pregnant. [2]
In healthy women, Postpartum thyroiditis can occur up to 1 year after delivery and should be differentiated from Hashimoto's thyroiditis as it is treated differently. [136] After giving birth, Tregs rapidly decrease and immune responses are re-established. It may lead to the occurrence or aggravation of autoimmune thyroid disease. [135]
Postpartum thyroiditis is believed to result from the modifications to the immune system necessary in pregnancy, and histologically is a subacute lymphocytic thyroiditis. The process is normally self-limiting, but when conventional antibodies are found there is a high chance of this proceeding to permanent hypothyroidism.
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
It is estimated that, typically, it takes from 12 to 40 years for autoimmune destruction to present symptoms. [2] However, there have been cases of isolated attacks as a result of drug reactions (i.e., use of blocking antibody ipilimumab ) [ 3 ] [ 4 ] or idiopathic events that have presented symptoms which may disappear after relatively short ...
Simmonds' disease, however, occurs in either sex due to causes unrelated to pregnancy. [15] However, in his 1939 publication, "Simmonds' Disease due to Post-partum Necrosis of the Anterior Pituitary", Sheehan displays post-partum necrosis as a cause of Simmonds' disease, thus establishing the relationship between the two conditions. [20]
For example, some autoimmune diseases tend to flare during pregnancy (possibly as an evolutionary mechanism to increase health protection for the child), [50] when hormone levels are high, and improve after menopause, when hormone levels decrease. Women may also naturally have autoimmune disease trigger events in puberty and pregnancy. [48]
There have been reports of fetal cells in the lining of the blood and thyroid glands of patients with autoimmune thyroid disease. These cells could become activated after delivery of the baby after immune suppression in the mother is lost, suggesting a role of fetal cells in the pathogenesis of such diseases. [40]