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2. Quetiapine - Wikipedia

   en.wikipedia.org/wiki/Quetiapine

   α 1-and α 2-adrenergic receptor antagonist; Histamine H 1 receptor antagonist; Muscarinic acetylcholine receptor antagonist; This means quetiapine is a dopamine, serotonin, and adrenergic antagonist, and a potent antihistamine with some anticholinergic properties. [76]

3. List of antidepressants - Wikipedia

   en.wikipedia.org/wiki/List_of_antidepressants

   Quetiapine (Seroquel) – approved as a monotherapy for bipolar depression; ... Gepirone (Exxua) – 5-HT 1A receptor partial agonist and α 2-adrenergic receptor ...

4. 5-HT2A receptor - Wikipedia

   en.wikipedia.org/wiki/5-HT2A_receptor

   Atypical antipsychotics – e.g., quetiapine, and asenapine are relatively potent antagonists of 5-HT 2A; Brexpiprazole – an atypical antipsychotic, is a potent antagonist at 5-HT 2A receptors (K i = 0.47 nM in humans). [99] [100] Cariprazine; Cyclobenzaprine – a strong antagonist of both 5-HT 2A and 5-HT 2C receptors; Cyproheptadine

5. Serotonin receptor antagonist - Wikipedia

   en.wikipedia.org/wiki/Serotonin_receptor_antagonist

   Quetiapine blocks 5-HT 2A, 5-HT 1A, dopamine receptors D 1 and D 2, histamine receptor H1, and A1 adrenoreceptors. 5-HT 2A/2C antagonists. Ketanserin Antihypertensive.

6. Adrenergic receptor - Wikipedia

   en.wikipedia.org/wiki/Adrenergic_receptor

   The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline) and epinephrine (adrenaline) produced by the body, but also many medications like beta blockers, beta-2 (β 2) antagonists and alpha-2 (α 2) agonists, which are used to treat high ...

7. Alpha-2 adrenergic receptor - Wikipedia

   en.wikipedia.org/wiki/Alpha-2_adrenergic_receptor

   The alpha-2 (α 2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the G i heterotrimeric G-protein. It consists of three highly homologous subtypes, including α 2A-, α 2B-, and α 2C-adrenergic. Some species other than humans express a fourth α 2D-adrenergic receptor as well. [1]