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  2. Disulfiram - Wikipedia

    en.wikipedia.org/wiki/Disulfiram

    Disulfiram is a medication used to support the treatment of chronic alcoholism by producing an acute sensitivity to ethanol (drinking alcohol). Disulfiram works by inhibiting the enzyme aldehyde dehydrogenase (specifically the ALDH2 enzyme [3]), causing many of the effects of a hangover to be felt immediately following alcohol consumption.

  3. Disulfiram-alcohol reaction - Wikipedia

    en.wikipedia.org/wiki/Disulfiram-alcohol_reaction

    Disulfiram-alcohol reaction (DAR) is the effect of the interaction in the human body of alcohol drunk with disulfiram or some types of mushrooms. [ 1 ] [ 2 ] The DAR is key to disulfiram therapy that is widely used for alcohol-aversive treatment and management of other addictions (e.g. cocaine [ 3 ] [ 4 ] use).

  4. Category:Disulfiram-like drugs - Wikipedia

    en.wikipedia.org/wiki/Category:Disulfiram-like_drugs

    Disulfiram-like drugs that produce sensitivity to the toxic effects of alcohol (drug). Mostly acetaldehyde dehydrogenase inhibitors. Subcategories.

  5. Disulfiram-like drug - Wikipedia

    en.wikipedia.org/wiki/Disulfiram-like_drug

    A number of drugs do not cause disulfiram-like reactions, but have other unintended interactions with alcoholic drinks. For example, alcohol interferes with the efficacy of erythromycin. Patients on linezolid and tedizolid may be sensitive to the tyramine present in tap beers and red wine. [8]

  6. Alcohol intolerance - Wikipedia

    en.wikipedia.org/wiki/Alcohol_intolerance

    [5] [6] It may also be characterized as intolerance causing hangover symptoms similar to the "disulfiram-like reaction" of aldehyde dehydrogenase deficiency or chronic fatigue syndrome. [ 7 ] [ 8 ] [ 9 ] Severe pain after drinking alcohol may indicate a more serious underlying condition.

  7. Thiuram disulfide - Wikipedia

    en.wikipedia.org/wiki/Thiuram_disulfide

    The tetramethyl derivative, known as thiram, is a widely used fungicide.The tetraethyl derivative, known as disulfiram, is commonly used to treat chronic alcoholism.It produces an acute sensitivity to alcohol ingestion by blocking metabolism of acetaldehyde by acetaldehyde dehydrogenase, leading to a higher concentration of the aldehyde in the blood, which in turn produces symptoms of a severe ...

  8. Couple offers advice after 70 years of marriage - AOL

    www.aol.com/news/couple-offers-advice-70-years...

    This month, they celebrated 70 years as husband and wife. Mrs. DeHaai offered this advice: "I'm afraid some people think when they get married they're joined at the hip, you know you've got to be ...

  9. Talk:Disulfiram - Wikipedia

    en.wikipedia.org/wiki/Talk:Disulfiram

    "Disulfiram is supplied in 200 mg, 250 mg, and 500 mg tablets. The usual initial dose is 500 mg for 1 to 2 weeks, followed by a maintenance dose of 250 mg (range 125 mg–500 mg) per day. The total daily dosage should not exceed 500 mg." This section has no references, and higher initial dosages are prescribed in some contries.