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  2. Avery–MacLeod–McCarty experiment - Wikipedia

    en.wikipedia.org/wiki/Avery–MacLeod–McCarty...

    Hyder, Avery, MacLeod and McCarty used strands of purified DNA such as this, precipitated from solutions of cell components, to perform bacterial transformations. The Avery–MacLeod–McCarty experiment was an experimental demonstration by Oswald Avery, Colin MacLeod, and Maclyn McCarty that, in 1944, reported that DNA is the substance that causes bacterial transformation, in an era when it ...

  3. Colin Munro MacLeod - Wikipedia

    en.wikipedia.org/wiki/Colin_Munro_MacLeod

    Colin Munro MacLeod (January 28, 1909 – February 11, 1972) was a Canadian-American geneticist. He was one of a trio of scientists who discovered that deoxyribonucleic acid, or DNA is responsible for the transformation of the physical characteristics of bacteria, which subsequently led to its identification as the molecule responsible for heredity.

  4. Rollin Hotchkiss - Wikipedia

    en.wikipedia.org/wiki/Rollin_Hotchkiss

    In 1946, in the wake of the Avery–MacLeod–McCarty experiment showing that DNA, not protein, had the power to transform bacteria from one type to another, Hotchkiss rejoined Avery's lab. His work on protein analysis helped answer Avery's critics who argued that the experiment was not sufficiently rigorous to rule out protein contamination ...

  5. Molecular Structure of Nucleic Acids: A Structure for ...

    en.wikipedia.org/wiki/Molecular_Structure_of...

    Watson and Crick used many aluminium templates like this one, which is the single base Adenine (A), to build a physical model of DNA in 1953. When Watson and Crick produced their double helix model of DNA, it was known that most of the specialized features of the many different life forms on Earth are made possible by proteins .

  6. Genetic transformation - Wikipedia

    en.wikipedia.org/wiki/Genetic_transformation

    They called this uptake and incorporation of DNA by bacteria "transformation" (See Avery-MacLeod-McCarty experiment) [4] The results of Avery et al.'s experiments were at first skeptically received by the scientific community and it was not until the development of genetic markers and the discovery of other methods of genetic transfer ...

  7. History of molecular biology - Wikipedia

    en.wikipedia.org/wiki/History_of_molecular_biology

    In 1944, Oswald Avery, working at the Rockefeller Institute of New York, demonstrated that genes are made up of DNA [3] (see Avery–MacLeod–McCarty experiment). In 1952, Alfred Hershey and Martha Chase confirmed that the genetic material of the bacteriophage, the virus which infects bacteria, is made up of DNA [4] (see Hershey–Chase ...

  8. Molecular biology - Wikipedia

    en.wikipedia.org/wiki/Molecular_biology

    The Avery–MacLeod–McCarty experiment was a landmark study conducted in 1944 that demonstrated that DNA, not protein as previously thought, carries genetic information in bacteria. Oswald Avery , Colin Munro MacLeod , and Maclyn McCarty used an extract from a strain of pneumococcus that could cause pneumonia in mice.

  9. Genetic engineering techniques - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering_techniques

    In 1928 Frederick Griffith proved the existence of a "transforming principle" involved in inheritance, which was identified as DNA in 1944 by Oswald Avery, Colin MacLeod, and Maclyn McCarty. Frederick Sanger developed a method for sequencing DNA in 1977, greatly increasing the genetic information available to researchers.