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Digoxin immune fab or digoxin-specific antibody is an antidote for overdose of digoxin. [3] It is made from immunoglobulin fragments from sheep that have already been immunized with a digoxin derivative, digoxindicarboxymethoxylamine (DDMA). Its brand names include Digibind (GlaxoSmithKline) and DigiFab (BTG plc).
An unusual side effect of digoxin is a disturbance of color vision (mostly yellow and green) called xanthopsia. Vincent van Gogh's "Yellow Period" may have somehow been influenced by concurrent digitalis therapy. Other oculotoxic effects of digoxin include generalized blurry vision, as well as seeing a "halo" around each point of light.
Digoxin (better known as Digitalis), sold under the brand name Lanoxin among others, is a medication used to treat various heart conditions. [4] Most frequently it is used for atrial fibrillation, atrial flutter, and heart failure. [4] Digoxin is one of the oldest medications used in the field of cardiology.
Digoxin immune Fab used to treat digoxin toxicity The primary treatment of digoxin toxicity is digoxin immune fab , which is an antibody made up of anti-digoxin immunoglobulin fragments. This antidote has been shown to be highly effective in treating life-threatening signs of digoxin toxicity such as hyperkalemia, hemodynamic instability, and ...
Digoxin Immune Fab is the antigen binding fragment of polyclonal antibodies raised to Digitalis derivative as a hapten bound to a protein and is used for the reversal of life-threatening digoxin or digitoxin toxicity. [1] [2] [3] Rho(D) immune globulin is made from pooled human plasma provided by Rh-negative donors with antibodies to the D antigen.
Digoxin Immune Fab antibody (Digibind and Digifab) Digoxin poisoning, Oleander ingestion [8] Diphenhydramine hydrochloride and benztropine mesylate: Extrapyramidal reactions associated with antipsychotics: 100% Ethanol or fomepizole: Ethylene glycol poisoning and methanol poisoning: Flumazenil: Benzodiazepine overdose: 100% oxygen or hyperbaric ...
Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia.It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting.
Digoxin immune fab; H. Heptavalent botulism antitoxin; S. Snake antivenom This page was last edited on 30 April 2013, at 18:34 (UTC). Text is available under the ...