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The presence of the GUS-induced color indicates where the gene has been actively expressed. In this way, strong promoter activity produces much staining and weak promoter activity produces less staining. The uidA gene can also be fused to a gene of interest, creating a gene fusion. The insertion of the uidA gene will cause production of GUS ...
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a n/a Wikidata View/Edit Human Glucagon is a peptide hormone, produced by alpha cells of the pancreas. It raises the concentration of glucose and fatty acids in the bloodstream and is considered to be the main catabolic hormone of the body. It is also used as a medication ...
Hypersensitive response (HR) is a mechanism used by plants to prevent the spread of infection by microbial pathogens.HR is characterized by the rapid death of cells in the local region surrounding an infection and it serves to restrict the growth and spread of pathogens to other parts of the plant.
Microgametogenesis is the process in plant reproduction where a microgametophyte develops in a pollen grain to the three-celled stage of its development. In flowering plants it occurs with a microspore mother cell inside the anther of the plant.
In 1982, they published their discovery that the gene for proglucagon actually codes for three peptides: glucagon and two novel peptides. [27] Those two novel peptides were later isolated, identified, and investigated by other researchers, and are now known as glucagon-like peptide-1 and glucagon-like peptide-2. [27]
This is why glucagon has been known for decades as a counter-regulatory hormone. [12] When blood glucose levels are low, the pancreas secretes glucagon, which in turn causes the liver to convert stored glycogen polymers into glucose monomers, which is then released into the blood. This process is called glycogenolysis.
Glucagon in the liver stimulates glycogenolysis when the blood glucose is lowered, known as hypoglycemia. [12] The glycogen in the liver can function as a backup source of glucose between meals. [2] Liver glycogen mainly serves the central nervous system. Adrenaline stimulates the breakdown of glycogen in the skeletal muscle during exercise. [12]
A missense mutation at 17q25 [11] in the GCGR gene is associated with diabetes mellitus type 2. [12] Inactivating mutation of glucagon receptor in humans causes resistance to glucagon and is associated with pancreatic alpha cell hyperplasia, nesidioblastosis, hyperglucagonemia, and pancreatic neuroendocrine tumors, also known as Mahvash disease ...