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2. Nicotine withdrawal - Wikipedia

   en.wikipedia.org/wiki/Nicotine_withdrawal

   Nicotine withdrawal is a group of symptoms that occur in the first few weeks after stopping or decreasing use of nicotine.Symptoms include intense cravings for nicotine, anger or irritability, anxiety, depression, impatience, trouble sleeping, restlessness, hunger, weight gain, and difficulty concentrating.

3. Nicotine dependence - Wikipedia

   en.wikipedia.org/wiki/Nicotine_dependence

   A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [21]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [9]

4. Smoking cessation - Wikipedia

   en.wikipedia.org/wiki/Smoking_cessation

   In recent years, especially in Canada and the United Kingdom, many smokers have switched to using electronic cigarettes to quit smoking tobacco. [16] [17] [18] However, a 2022 study found that 20% of smokers who tried to use e-cigarettes to quit smoking succeeded but 66% of them ended as dual users of cigarettes and vape products one year out. [19]

5. Nicotine - Wikipedia

   en.wikipedia.org/wiki/Nicotine

   Mild nicotine withdrawal symptoms are measurable in unrestricted smokers, who experience normal moods only as their blood nicotine levels peak, with each cigarette. [35] On quitting, withdrawal symptoms worsen sharply, then gradually improve to a normal state. [35] Nicotine use as a tool for quitting smoking has a good safety history. [36]

6. Nicotine replacement therapy - Wikipedia

   en.wikipedia.org/wiki/Nicotine_replacement_therapy

   Using nicotine replacement therapy to quit smoking should be considered for people who are severely dependent on nicotine. [21] People who are severely dependent include those who smoke: more than one pack per day, within five minutes of awakening, while ill, when they wake up in the middle of the night, to ease withdrawal signs and symptoms. [21]

7. Effects of nicotine on human brain development - Wikipedia

   en.wikipedia.org/wiki/Effects_of_nicotine_on...

   The ability to quitting smoking is affected by genetic factors, including genetically based differences in the way nicotine is metabolized. [48] In the CYP450 system there are 173 genetic variants, which impacts how quickly nicotine is metabolizes by each individual. [49] The speed of metabolism impacts the regularity and quantity of nicotine ...