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  2. Mutation - Wikipedia

    en.wikipedia.org/wiki/Mutation

    A germline mutation in the reproductive cells of an individual gives rise to a constitutional mutation in the offspring, that is, a mutation that is present in every cell. A constitutional mutation can also occur very soon after fertilization, or continue from a previous constitutional mutation in a parent. [90]

  3. Mutation rate - Wikipedia

    en.wikipedia.org/wiki/Mutation_rate

    Secondly, higher mutation rates increase the rate of beneficial mutations, and evolution may prevent a lowering of the mutation rate in order to maintain optimal rates of adaptation. [ 28 ] [ 29 ] As such, hypermutation enables some cells to rapidly adapt to changing conditions in order to avoid the entire population from becoming extinct. [ 30 ]

  4. Point mutation - Wikipedia

    en.wikipedia.org/wiki/Point_mutation

    An advantageous mutation can create an advantage for that organism and lead to the trait's being passed down from generation to generation, improving and benefiting the entire population. The scientific theory of evolution is greatly dependent on point mutations in cells. The theory explains the diversity and history of living organisms on Earth.

  5. Genetic variation - Wikipedia

    en.wikipedia.org/wiki/Genetic_variation

    Random mutations are the ultimate source of genetic variation. Mutations are likely to be rare, and most mutations are neutral or deleterious, but in some instances, the new alleles can be favored by natural selection. Polyploidy is an example of chromosomal mutation. Polyploidy is a condition wherein organisms have three or more sets of ...

  6. Somatic evolution in cancer - Wikipedia

    en.wikipedia.org/wiki/Somatic_evolution_in_cancer

    Somatic evolution is the accumulation of mutations and epimutations in somatic cells (the cells of a body, as opposed to germ plasm and stem cells) during a lifetime, and the effects of those mutations and epimutations on the fitness of those cells.

  7. Germline mutation - Wikipedia

    en.wikipedia.org/wiki/Germline_mutation

    A germline mutation, or germinal mutation, is any detectable variation within germ cells (cells that, when fully developed, become sperm and ova). [1] Mutations in these cells are the only mutations that can be passed on to offspring, when either a mutated sperm or oocyte come together to form a zygote . [ 2 ]

  8. Evolution of cells - Wikipedia

    en.wikipedia.org/wiki/Evolution_of_cells

    Evolution of cells refers to the evolutionary origin and subsequent evolutionary development of cells. Cells first emerged at least 3.8 billion years ago [ 1 ] [ 2 ] [ 3 ] approximately 750 million years after Earth was formed.

  9. Mutagenesis - Wikipedia

    en.wikipedia.org/wiki/Mutagenesis

    In nature, the mutations that arise may be beneficial or deleterious—this is the driving force of evolution. An organism may acquire new traits through genetic mutation, but mutation may also result in impaired function of the genes and, in severe cases, causes the death of the organism.