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Fluconazole therapy has been associated with QT interval prolongation, which may lead to serious cardiac arrhythmias. Thus, it is used with caution in patients with risk factors for prolonged QT interval, such as electrolyte imbalance or use of other drugs that may prolong the QT interval (particularly cisapride and pimozide). [24]
Fosfluconazole (INN Tooltip International Nonproprietary Name) is a water-soluble phosphate prodrug of fluconazole [1] — a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
Rezafungin, sold under the brand name Rezzayo (by Melinta Therapeutics), is a medication used for the treatment of invasive candidiasis. [2] It is an echinocandin antifungal [1] [4] that acts as a fungal β-glucan synthase inhibitor.
The medication will be sold under the brand name ... "This action and the agency’s designations to expedite the drug’s development and review underscore FDA’s commitment to approving safe ...
Oteseconazole has exhibited an outstanding tolerability profile and a low occurrence of adverse effects in clinical trials. In a phase 3 study, the incidence of treatment-emergent adverse events (TEAEs) was comparable between the oteseconazole and fluconazole/placebo groups, with the majority of TEAEs being of mild or moderate severity. [9]
Before oral antifungal therapies are used to treat nail disease, a confirmation of the fungal infection should be made. [36] Approximately half of suspected cases of fungal infection in nails have a non-fungal cause. [36] The side effects of oral treatment are significant and people without an infection should not take these drugs. [36]
Voriconazole, sold under the brand name Vfend among others, is an antifungal medication used to treat a number of fungal infections. [5] This includes aspergillosis, candidiasis, coccidioidomycosis, histoplasmosis, penicilliosis, and infections by Scedosporium or Fusarium. [5] It can be taken by mouth or used by injection into a vein. [5]
Adult: Per tablet contains flupentixol 0.5 mg and melitracen 10 mg: 1 tablet in the morning and at midday. May double morning dose in severe cases. May double morning dose in severe cases. Not to exceed 4 tablets daily.