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  2. Decitabine - Wikipedia

    en.wikipedia.org/wiki/Decitabine

    Decitabine (i.e., 5-aza-2′-deoxycytidine), sold under the brand name Dacogen among others, acts as a nucleic acid synthesis inhibitor. [4] It is a medication for the treatment of myelodysplastic syndromes , a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML). [ 5 ]

  3. Decitabine/cedazuridine - Wikipedia

    en.wikipedia.org/wiki/Decitabine/cedazuridine

    Decitabine/cedazuridine, sold under the brand name Inqovi among others, is a fixed-dose combination anticancer medication used for the treatment of adults with myelodysplastic syndromes and chronic myelomonocytic leukemia (CMML).

  4. Demethylating agent - Wikipedia

    en.wikipedia.org/wiki/Demethylating_agent

    Both compounds have been approved in the treatment of myelodysplastic syndrome (MDS) by Food and Drug Administration (FDA) in United States. Azacitidine and decitabine are marketed as Vidaza and Dacogen respectively. Azacitidine is the first drug to be approved by FDA for treating MDS and has been given orphan drug status.

  5. Azacitidine - Wikipedia

    en.wikipedia.org/wiki/Azacitidine

    Azacitidine is indicated for the treatment of myelodysplastic syndrome, [4] for which it received approval by the U.S. Food and Drug Administration (FDA) on 19 May 2004. [11] [4] [12] In two randomized controlled trials comparing azacitidine to supportive treatment, 16% of subjects with myelodysplastic syndrome who were randomized to receive azacitidine had a complete or partial normalization ...

  6. Hypomethylating agent - Wikipedia

    en.wikipedia.org/wiki/Hypomethylating_agent

    A hypomethylating agent (or demethylating agent [1]) is a drug that inhibits DNA methylation: the modification of DNA nucleotides by addition of a methyl group.Because DNA methylation affects cellular function through successive generations of cells without changing the underlying DNA sequence, treatment with a hypomethylating agent is considered a type of epigenetic therapy.

  7. Prescriptions for weight loss drugs are skyrocketing ... - AOL

    www.aol.com/prescriptions-weight-loss-drugs...

    The use of blockbuster weight loss drugs has surged among young women, for whom the treatments can often be "liberating." Prescriptions for weight loss drugs are skyrocketing, especially among ...

  8. What you should know about the latest obesity medication ...

    www.aol.com/news/obesity-medication-zepbound...

    Dr. Leana Wen: Both are injection medications that are intended to be used once a week. They were both first approved to treat type 2 diabetes, and clinical trials also showed that they induced a ...

  9. Venetoclax - Wikipedia

    en.wikipedia.org/wiki/Venetoclax

    Venetoclax is also indicated as part of a combination therapy for acute myeloid leukemia (AML). [7] For this purpose it is used with azacitidine, decitabine, or low-dose cytarabine for newly diagnosed adults who are age 75 years or older, or those with other health problems where intensive chemotherapy cannot be used.

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