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The amygdalin found in apricot seeds has been marketed as an alternative cancer treatment; however, studies have shown it to be ineffective in treating cancer. [3] Cancer Council Australia have commented that "eating apricot kernels in large amounts is not only ineffective for treating cancer, but could also be very dangerous".
Eating amygdalin will cause it to release cyanide in the human body, and may lead to cyanide poisoning. [1] Since the early 1950s, both amygdalin and a chemical derivative named laetrile have been promoted as alternative cancer treatments, often under the misnomer vitamin B 17 (neither amygdalin nor laetrile is a vitamin). [2]
Ernst Theodore Krebs Jr. (May 17, 1911 – September 8, 1996) was an American promoter of various substances as alternative cures for cancer, including pangamic acid and amygdalin. He also co-patented the semi-synthetic chemical compound closely related to amygdalin called laetrile , which was also promoted as a cancer preventative and cure.
Amygdalin, sometimes incorrectly referred to as vitamin B17; Boron-17 (B-17 or 17 B), an isotope of boron; HLA-B17, an HLA - B serotype gene; B17, the Steinitz variation of the Caro-Kann Defence's code from the Encyclopaedia of Chess Openings "Please Mr. Please", song about a song in slot B-17 of a jukebox
The enzyme amygdalin β-glucosidase (EC 3.2.1.117) catalyzes the following chemical reaction: ( R ) - amygdalin + H 2 O ⇌ {\displaystyle \rightleftharpoons } ( R )-prunasin + D -glucose Thus, the two substrates of this enzyme are ( R )- amygdalin and H 2 O , whereas its two products are ( R )- prunasin and D - glucose .
Examples include amygdalin and prunasin which are made by the bitter almond tree; other species that produce cyanogenic glycosides are sorghum (from which dhurrin, the first cyanogenic glycoside to be identified, was first isolated), barley, flax, white clover, and cassava, which produces linamarin and lotaustralin.
In almonds, the amygdalin biosynthetic genes are expressed at different levels in the tegument (mother tissue, or outer section) and cotyledon (kernel, or father tissue), and vary significantly during almond ontogeny. [1] [6] [7] The biosynthesis of prunasin occurs in the tegument, then transported to other tissues for conversion to amygdalin ...
Once had the researcher to carry on a series of studies on the antitumor activity of amygdalin, and 36 different studies involving amygdalin administration were also analyzed (Milazzo et al., 2011). The results showed that there was no reliable clinical data to support the claim that amygdalin have beneficial effects for cancer patients ...
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