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In particular, quinoline-type drugs are known to be ototoxic. Examples include chloroquine and hydroxychloroquine which are quinine-like. Apart from antimalarial effects, these drugs are also used in the treatment of other diseases such as dermatological, immunological, rheumatological, and severe infectious diseases. [25]
At high doses, quinine, aspirin and other salicylates may also cause high-pitch tinnitus and hearing loss in both ears, typically reversible upon discontinuation of the drug. [20] Erectile dysfunction medications may have the potential to cause hearing loss. [36] However the link between erectile dysfunction medications and hearing loss remains ...
Ototoxic drugs also may cause subjective tinnitus, as they may cause hearing loss, [15] or increase the damage done by exposure to loud noise. [39] This damage may occur even at doses not considered ototoxic. [40] More than 260 medications have been reported to cause tinnitus as a side effect. [41]
Cause skin photosensitivity, [19] so exposure to the sun or intense light is not recommended; Cause drug-induced lupus, and hepatitis; Cause microvesicular fatty liver [20] Cause tinnitus [21] [22] Cause epigastric pain [19] Interfere with methotrexate by displacing it from the various protein-binding sites
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Aminoglycosides can cause inner ear toxicity which can result in sensorineural hearing loss. [19] The incidence of inner ear toxicity varies from 7 to 90%, depending on the types of antibiotics used, susceptibility of the patient to such antibiotics, and the duration of antibiotic administration. [20]
Antibiotics are some of the most powerful tools in medicine. They’re prescribed to treat a variety of infections caused by bacteria, such as urinary tract infections, most ear infections, strep ...
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