Search results
Results From The WOW.Com Content Network
Heparin, also known as unfractionated heparin (UFH), is a medication and naturally occurring glycosaminoglycan. [3] [4] Heparin is a blood anticoagulant that increases the activity of antithrombin. [5] It is used in the treatment of heart attacks and unstable angina. [3] It can be given intravenously or by injection under the skin. [3]
Heparin was first isolated from dog liver by medical student Jay McClean in 1916. Jorpes discovered the structure of the heparin polysaccharide in 1935, identifying that it is a highly sulfated polymer of glycosaminoglycoglycan (GAG) and uronic acid.
Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor is synthesized as a membrane-anchored mitogenic and chemotactic glycoprotein. An epidermal growth factor produced by monocytes and macrophages, due to an affinity for heparin is
566 n/a Ensembl ENSG00000278624 ENSG00000172232 n/a UniProt P20160 n/a RefSeq (mRNA) NM_001700 n/a RefSeq (protein) NP_001691 n/a Location (UCSC) Chr 19: 0.83 – 0.83 Mb n/a PubMed search n/a Wikidata View/Edit Human Azurocidin also known as cationic antimicrobial protein CAP37 or heparin-binding protein (HBP) is a protein that in humans is encoded by the AZU1 gene. Function Azurophil ...
Structure formula of one of the many sulfation patterns of the heparan sulfate subunit. Heparan sulfate (HS) is a linear polysaccharide found in all animal tissues. [1] It occurs in a proteoglycan (HSPG, i.e. Heparan Sulfate ProteoGlycan) in which two or three HS chains are attached in close proximity to cell surface or extracellular matrix proteins.
Low-molecular-weight heparin (LMWH) is a class of anticoagulant medications. [1] They are used in the prevention of blood clots and, in the treatment of venous thromboembolism (deep vein thrombosis and pulmonary embolism), and the treatment of myocardial infarction.
Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count), due to the administration of various forms of heparin, an ...
Heparin mimicking polymers can be synthesized through a variety of mechanisms. To begin, monomers can be either synthesized or purchased from avenues such as Sigma Aldrich. The monomers are the basic subunits of the polymer and can be designed to incorporate specific functional groups, e.g. sugars , urea , which can enhance the biocompatibility ...