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The ability to use historical records to trace the spread and treatment of leprosy in antiquity is greatly limited by confusion over which skin diseases were being discussed. [8] Famously, the "leprosy" of most translations of the Bible as far back as the Septuagint represents a multilayered historical process of confusion.
Leprosy has historically been associated with social stigma, which continues to be a barrier to self-reporting and early treatment. [4] Leprosy is classified as a neglected tropical disease. [21] World Leprosy Day was started in 1954 to draw awareness to those affected by leprosy. [22] [4] The study of leprosy and its treatment is known as ...
Rea and his colleague Robert Modlin researched the role the immune system played in symptoms of leprosy, which led to the development of new treatments for the disease that rendered it non-contagious and allowed leprosy patients to live normal lives. [2] Rea also supported the use of thalidomide to treat a complication of leprosy. [2]
The diffuse leprosy of Lucio and Latapí, also known as diffuse lepromatous leprosy or "pretty leprosy", is a clinical variety of lepromatous leprosy. It was first described by Lucio and Alvarado in 1852 and re-identified by Latapí in 1936. It is common in Mexico (23% of leprosy cases) and in Costa Rica and very rare in other countries.
Other severe skin diseases were frequently conflated with leprosy and all such sufferers were kept away from the general public, although some religious orders provided medical care and treatment. Recent research has shown M. leprae has maintained a similarly virulent genome over at least the last thousand years, leaving it unclear which ...
Mycobacterium leprae (also known as the leprosy bacillus or Hansen's bacillus) is one [a] of the two species of bacteria that cause Hansen's disease (leprosy), [1] a chronic but curable infectious disease that damages the peripheral nerves and targets the skin, eyes, nose, and muscles.
Aldo Castellani was the first to prepare a substance similar to lepromin while attempting to produce a leprosy vaccine. [6] [7] Kensuke Mitsuda worked with lepromin starting in 1916 and published the first paper on it in 1919 [8] However, he retained Ernest Reinhold Rost's earlier name leprolin and his original idea was to find a test that distinguishes leprosy patients from non-leprosy persons.
Leprosy, Paget's disease of bone Leonine facies is a facies that resembles that of a lion . It is seen in multiple conditions and has been classically described for lepromatous leprosy as well as Paget's disease of bone .