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Polypyrimidine tract-binding protein, also known as PTB or hnRNP I, is an RNA-binding protein. PTB functions mainly as a splicing regulator, although it is also involved in alternative 3' end processing, mRNA stability and RNA localization. [ 1 ]
Advanced Placement (AP) Biology (also known as AP Bio) is an Advanced Placement biology course and exam offered by the College Board in the United States. For the 2012–2013 school year, the College Board unveiled a new curriculum with a greater focus on "scientific practices". [1]
The PTB domains facilitate interaction with the activated tyrosine-phosphorylated insulin receptor. The PTB domain is situated towards the N terminus . Two arginines in this domain are responsible for hydrogen bonding phosphotyrosine residues on an Ac -LYASSNPApY- NH2 peptide in the juxtamembrane region of the insulin receptor.
This is an accepted version of this page This is the latest accepted revision, reviewed on 5 March 2025. American politician (born 1981) This article needs more complete citations for verification. Please help add missing citation information so that sources are clearly identifiable. (February 2025) (Learn how and when to remove this message) Tulsi Gabbard Gabbard in 2025 8th Director of ...
Cell Biology in "The Biology Project" of University of Arizona. Centre of the Cell online; The Image & Video Library of The American Society for Cell Biology Archived 2011-06-10 at the Wayback Machine, a collection of peer-reviewed still images, video clips and digital books that illustrate the structure, function and biology of the cell.
The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum (ER) stress. [1] It has been found to be conserved between mammalian species, [2] as well as yeast [1] [3] and worm organisms. The UPR is activated in response to an accumulation of unfolded or misfolded proteins in the lumen of the
A phase response curve (PRC) illustrates the transient change (phase response) in the cycle period of an oscillation induced by a perturbation as a function of the phase at which it is received. PRCs are used in various fields; examples of biological oscillations are the heartbeat, circadian rhythms , and the regular, repetitive firing observed ...
The foundation's original funding included $1.2 million from Gaga, $500,000 from the MacArthur Foundation, and $850,000 from Barneys New York. [407] In July 2012, the BTWF partnered with Office Depot for a series of limited edition back-to-school products, with 25% of its sales going towards the foundation, for a guaranteed donation of $1 ...