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Symptoms. High anion gap. Causes and diagnosis. Treatment. Outlook. A low anion gap may occur with some health conditions, including liver or kidney disease, burns, and certain types of...
If your blood results reveal a low anion gap, it may mean you have a lower-than-normal level of albumin (hypoalbuminemia). Albumin is an essential protein in your blood. Low albumin may indicate the following conditions:
A low anion gap results from an imbalance in the body’s pH levels. Healthcare professionals identify this “gap” by examining the results of a blood test that measures electrolyte...
Hypoalbuminemia: Low levels of albumin in the blood can contribute to a low anion gap. Multiple Myeloma: This type of cancer can affect the balance of electrolytes in the body, leading to a low anion gap. Hypercalcemia: High levels of calcium in the blood can cause a decrease in the anion gap.
Low anion gap symptoms include nausea; vomiting; confusion; lightheadedness; hand tremors; numbness or tingling in the face, hands, or feet; and muscle spasms. What level of anion gap...
A low anion gap is rare. It may indicate low albumin levels — a sign of inflammation — but doctors usually order a second test to check the result in case of error.
In this article, we review the constituents of the anion gap, build a differential diagnosis for a low anion gap using case examples, and provide a stepwise approach to diagnostic testing to evaluate this abnormal finding.
The anion gap is a value calculated from the results of an electrolyte blood test which informs clinicians about the balance of positively and negatively charged particles in the blood. This is a useful measure to diagnose diseases and disorders associated with an acid/base imbalance in the body.
The most common cause of a low anion gap is a low level of albumin, a protein in the blood. Low albumin may be a sign of not eating enough protein, kidney problems, liver disease, heart disease, or some types of cancer. Learn more about laboratory tests, reference ranges, and understanding results.
Normal results are 4 to 12 mEq/L, although the normal level may vary from by lab. If your results are higher, it may mean that you have metabolic acidosis. Hypoalbuminemia means you have less albumin protein than normal. If you have this condition, your expected normal result must be lower.