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  2. Nebivolol - Wikipedia

    en.wikipedia.org/wiki/Nebivolol

    The drug is highly cardioselective at 5 mg. [19] In addition, at doses above 10 mg, nebivolol loses its cardioselectivity and blocks both β1 and β2 receptors, [18] while the recommended starting dose of nebivolol is 5 mg, sufficient control of blood pressure may require doses up to 40 mg. [18] Furthermore, nebivolol is also not ...

  3. Amlodipine - Wikipedia

    en.wikipedia.org/wiki/Amlodipine

    Amlodipine has been studied in healthy volunteers following oral administration of 14 C-labelled drug. [53] Amlodipine is well absorbed by the oral route with a mean oral bioavailability around 60%; the half-life of amlodipine is about 30 h to 50 h, and steady-state plasma concentrations are achieved after 7 to 8 days of daily dosing. [7]

  4. Daridorexant - Wikipedia

    en.wikipedia.org/wiki/Daridorexant

    [5] [7] The half-life of daridorexant may be longer in elderly individuals compared to young adults (9–10 hours in the elderly versus 6 hours in young adults). [7] Its half-life is shorter than that of other orexin receptor antagonists such as suvorexant (12 hours) and lemborexant (~18–55 hours). [5]

  5. Biological half-life - Wikipedia

    en.wikipedia.org/wiki/Biological_half-life

    Mercury (as methylmercury) in the body has a half-life of about 65 days. Lead in the blood has a half life of 28–36 days. [29] [30] Lead in bone has a biological half-life of about ten years. Cadmium in bone has a biological half-life of about 30 years. Plutonium in bone has a biological half-life of about 100 years.

  6. Statins are Effective Even for People Over Age 75, What ... - AOL

    www.aol.com/statins-effective-even-people-over...

    A new study finds even people over age 75 can get heart benefits from statins. ... The participants were split into three groups: People between the ages of 60 and 74, 75 to 84, and 85 and older. ...

  7. Ramipril - Wikipedia

    en.wikipedia.org/wiki/Ramipril

    Ramipril, a prodrug or precursor drug, is converted to the active metabolite ramiprilat by carboxylesterase 1. [17] [18] Ramiprilat is mostly excreted by the kidneys. Its half-life is variable (3–16 hours), and is prolonged by heart and liver failure, as well as kidney failure. Peak effect occurs between 3 and 6 hours after dosing, with ...

  8. Top aging expert says these 4 FDA-approved drugs hold promise ...

    www.aol.com/finance/global-aging-doctor-says-4...

    The drugs, while used to treat diabetes, show promise in reducing the risk of age-related diseases and kidney disease, by reducing oxidative stress and inflammation, and improving heart health and ...

  9. 5 supplements a doctor who says he's reversed his age by 20 ...

    www.aol.com/5-supplements-doctor-says-hes...

    Dr. Michael Roizen is 78 but says his biological age is 57.6. Roizen, who has written about longevity, takes supplements every day. They include multivitamins and aspirin.