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Normally, the blockage should affect approximately 70% of the artery for symptoms to become noticeable. [3] Symptoms can be less severe during gradual narrowing, as this allows time for the widening of existing vessels and the formation of new ones ( collateral vessels ), allowing blood to still reach the area.
The prevalence of PAD in the general population is 3–7%, affecting up to 20% of those over 70; [85] 70%–80% of affected individuals are asymptomatic; only a minority ever require revascularization or amputation. [citation needed] Peripheral artery disease affects one in three diabetics over the age of 50. In the US, it affects 12–20 ...
Atherosclerosis symptoms can depend on which arteries are blocked and the severity of your blockage. For many people, it progresses silently. ... It most commonly affects your legs. Symptoms can ...
Symptoms classically affect a leg and typically develop over hours or days, [20] though they can develop suddenly or over a matter of weeks. [21] The legs are primarily affected, with 4–10% of DVT occurring in the arms. [11] Despite the signs and symptoms being highly variable, [5] the typical symptoms are pain, swelling, and redness.
Symptoms of the narrowing are pain and numbness within the arms or legs. Another significant location for plaque formation is the renal arteries , which supply blood to the kidneys. Plaque occurrence and accumulation lead to decreased kidney blood flow and chronic kidney disease , which, like in all other areas, is typically asymptomatic until ...
The major tissues affected are nerves and muscles, where irreversible damage starts to occur after 4–6 hours of cessation of blood supply. [4] Skeletal muscle, the major tissue affected, is still relatively resistant to infarction compared to the heart and brain because its ability to rely on anaerobic metabolism by glycogen stored in the cells may supply the muscle tissue long enough for ...
In one study, 70% of women who had a heart attack reported this. “It is a significant fatigue that really feels different than just tiredness at the end of a busy day,” says Rosen.
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