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The pathophysiology of tuberculous meningitis involves bacterial invasion of the brain parenchyma meninges or cortex, causing the formation of small subpial foci. These foci, termed Rich foci, are necrotic and expand as the colonies within them multiply.
Most infections show no symptoms, in which case it is known as latent tuberculosis. [1] Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. [1] Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. [1]
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M. tuberculosis in the lungs, showing large cavities the bacteria have dissolved. Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis.
Tuberculosis verrucosa cutis is a rash of small, red papules and nodules in the skin that may appear two to four weeks after inoculation by Mycobacterium tuberculosis in a previously infected and immunocompetent individual.
Tuberculosis creates cavities visible in x-rays like this one in the patient's right upper lobe.. A posterior-anterior (PA) chest X-ray is the standard view used; other views (lateral or lordotic) or CT scans may be necessary.
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