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To probe insular neural circuits, Gogolla and her lab use in vivo two-photon calcium imaging to record neural activity while mice are processing emotionally relevant stimuli, and they further use innovative behavioral assays, optogenetic techniques, and machine learning algorithms to link neural activity to behavior, manipulate neural circuits ...
The underconnectivity theory of autism posits that autistic people tend to have fewer high-level neural connections and less global synchronization, along with an excess of low-level processes. [31] Functional connectivity studies have found both hypo- and hyperconnectivity in brains of autistic people. [ 32 ]
Neural binding is the neuroscientific aspect of what is commonly known as the binding problem: the interdisciplinary difficulty of creating a comprehensive and verifiable model for the unity of consciousness. "Binding" refers to the integration of highly diverse neural information in the forming of one's cohesive experience.
Matthew Belmonte is a reader in psychology at Nottingham Trent University who researches the behavior and neurophysiology of autistic individuals. [1] He has studied the behavioral aspects of autism by providing subjects with videogames that measure several perceptual properties. [2]
Warren McCulloch and Walter Pitts (1943) were the first to suggest that neural activity is computational. They argued that neural computations explain cognition . [ 2 ] The theory was proposed in its modern form by Hilary Putnam in 1960 and 1961, [ 3 ] and then developed by his PhD student, philosopher, and cognitive scientist Jerry Fodor in ...
Research using an animal model of obsessive-compulsive disorder employed a standardized paradigm where the behavior of rats in a large open field was video recorded for 55 min on each test. Rat Macroscopic Video Obsessive-compulsive disorder No [2] Allen Brain Atlas: Atlas, stained sections from brains showing development and gene expression
Jacqueline N. Crawley (née Lerner) is an American behavioral neuroscientist and an expert on rodent behavioral analysis. [1] Since July 2012, she is the Robert E. Chason Chair in Translational Research in the MIND Institute and professor of psychiatry and behavioral sciences at the University of California, Davis School of Medicine in Sacramento. [2]
However, because of the multigene involvement in autism, the MECP2 gene has only been identified as a vulnerability factor in autism. [63] The most current model illustrating MECP2 is known as the transcriptional activator model. Another potential molecular convergence involves the early growth response gene-2 (EGR2). [60]