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Use during pregnancy or breastfeeding does not appear to be harmful to the fetus. [4] [6] [7] It can be used in children and those over 65 years of age. [4] Those with kidney problems may require a decrease in dose. [4] Cefalexin was developed in 1967. [8] [9] [10] It was first marketed in 1969 under the brand name Keflex.
However, not all of them are safe to use during pregnancy. One of the components of bismuth subsalicylate is salicylate, which is a component that crosses the placenta. Due to this, there is an increased risk for intrauterine growth retardation, fetal hemorrhage, and maternal hemorrhage within organogenesis and in the second/third trimester. [ 12 ]
[108] [107] Cephalexin or nitrofurantoin are typically used because they are generally considered safe in pregnancy. [107] A kidney infection during pregnancy may result in preterm birth or pre-eclampsia (a state of high blood pressure and kidney dysfunction during pregnancy that can lead to seizures ). [ 42 ]
The growing popularity of drugs like Ozempic, Mounjaro and Wegovy, designed to help people with Type 2 diabetes and obesity, has raised new questions about what those drugs could mean for ...
Acetaminophen has long been considered safe to help reduce fever and relieve pain while pregnant. Here's what experts say about new claims.
In contrast, paracetamol (acetaminophen) is regarded as being safe and well tolerated during pregnancy, but Leffers et al. released a study in 2010, indicating that there may be associated male infertility in the unborn. [92] [93] Doses should be taken as prescribed, due to risk of liver toxicity with overdoses. [94]
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Use in the later part of pregnancy or during breastfeeding is not recommended. [7] [1] Celecoxib was patented in 1993 and came into medical use in 1999. [12] It is available as a generic medication. [13] In 2022, it was the 93rd most commonly prescribed medication in the United States, with more than 7 million prescriptions. [14] [15]