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Protein phosphatase 2 (PP2), also known as PP2A, is an enzyme that in humans is encoded by the PPP2CA gene. [ 2 ] [ 3 ] The PP2A heterotrimeric protein phosphatase is ubiquitously expressed, accounting for a large fraction of phosphatase activity in eukaryotic cells. [ 4 ]
The main discussion of these abbreviations in the context of drug prescriptions and other medical prescriptions is at List of abbreviations used in medical prescriptions. Some of these abbreviations are best not used, as marked and explained here.
List of medical abbreviations: Overview; List of medical abbreviations: Latin abbreviations; List of abbreviations for medical organisations and personnel; List of abbreviations used in medical prescriptions; List of optometric abbreviations
Past medical history (see also medical history) PSI: Pneumonia severity index: PSP: phenylsulphtalein: PSS: progressive systemic sclerosis (see scleroderma) PSVT: paroxysmal supraventricular tachycardia: PT: prothrombin time physical therapy (physiotherapy) Pt. patient (from Latin patiens, meaning "one who endures" or "one who suffers") PTA
Protein phosphatase 2A (PP2A) is a major intracellular protein phosphatase that regulates multiple aspects of cell growth and metabolism.Phosphorylation enables the activation or The ability of this widely distributed heterotrimeric enzyme to act on a diverse array of substrates is largely controlled by the nature of its regulatory B subunit.
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I 1 PP2A has a highly acidic C-terminal tail and the N-terminus is leucine/isoleucine rich (Li et al., 1996). In the presence of physiological conditions of Mn 2+, I 1 PP2A can also associate with and stimulate the activity of PP1 but Mn 2+ also does not affect the inhibition of PP2A through I 1 PP2A, in vitro (Janssens & Goris, 2001).