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Furosemide is a known ototoxic agent generally causing transient hearing loss but can be permanent. Reported cases of furosemide-induced hearing loss appeared to be associated with rapid intravenous administration, high dosages, concomitant renal disease, and coadministration with other ototoxic medication.
Ototoxicity-induced hearing loss typically impacts the high frequency range, affecting above 8000 Hz prior to impacting frequencies below. [8] There is not global consensus on measuring severity of ototoxicity-induced hearing loss as there are many criteria available to define and measure ototoxicity-induced hearing loss.
Studies have proven that high-dose usage of aspirin can be associated with ototoxicity, manifesting reversible hearing loss and tinnitus. [20] The underlying mechanism is associated with a change in isolated cochlear outer hair cells (OHCs). Due to the COX inhibition, there is an increasing amount of leukotrienes in the inner ear. This ...
Hearing loss due to chemicals starts in the high-frequency range and is irreversible. It damages the cochlea with lesions and degrades central portions of the auditory system. [45] For some ototoxic chemical exposures, particularly styrene, [46] the risk of hearing loss can be higher than being exposed to noise alone.
“Anything that can cause hearing loss can actually lead to tinnitus, because the underlying pathophysiology might be similar,” Deshpande said. “So commonsense precautions of preventing ...
Hearing loss has multiple causes, including ageing, genetics, perinatal problems and acquired causes like noise and disease. For some kinds of hearing loss the cause may be classified as of unknown cause. [citation needed] There is a progressive loss of ability to hear high frequencies with aging known as presbycusis. For men, this can start as ...
Loss of hearing. Priapism. Sildenafil could also cause an increased risk of heart attack or other heart problems. ... hearing loss, vision loss, an allergic reaction, Peyronie’s disease, or ...
Complete loss of the stereocilia causes permanent hearing damage and is more associated with noise-induced hearing loss and other auditory diseases. The outer hair cells, or OHCs, can be thought of as microamplifiers that provide stimulation to the inner hair cells. The OHCs are the most fragile of the hair cells, hence their involvement in ...