Search results
Results From The WOW.Com Content Network
The Schaffer collateral is located between the CA3 region and CA1 region in the hippocampus. Schaffer collaterals are the axons of pyramidal cells that connect two neurons (CA3 and CA1) and transfer information from CA3 to CA1. [5] [6] The entorhinal cortex sends the main input to the dentate gyrus (perforant pathway).
The function of neurons depends upon cell polarity. The distinctive structure of nerve cells allows action potentials to travel directionally (from dendrites to cell body down the axon), and for these signals to then be received and carried on by post-synaptic neurons or received by effector cells. Nerve cells have long been used as models for ...
Calcium entry into the cell causes more prolonged depolarization and increased action potentials. Usually curtailed by the hyperpolarizing local inhibition (due to the excitatory collateral system), this can lead to gradual recruitment of CA3 neurons and result in synchronized burst discharges. [2]
Axons usually make contact with other neurons at junctions called synapses but can also make contact with muscle or gland cells. In some circumstances, the axon of one neuron may form a synapse with the dendrites of the same neuron, resulting in an autapse .
Much of the synchronous bursting activity associated with interictal epileptiform activity appears to be generated in CA3. Its excitatory collateral connectivity seems to be mostly responsible for this. CA3 uniquely, has pyramidal cell axon collaterals that ramify extensively with local regions and make excitatory contacts with them.
The densely distributed neurons of the pars compacta have larger and thicker dendritic arborizations than those of the pars reticulata and lateralis. The ventral dendrites descending in the pars reticulata receives inhibitory synapses from the initial axonal collaterals of pars reticulata neurons (Hajos and Greefield, 1994).
The trisynaptic circuit is a neural circuit in the hippocampus, which is made up of three major cell groups: granule cells in the dentate gyrus, pyramidal neurons in CA3, and pyramidal neurons in CA1. The hippocampal relay involves three main regions within the hippocampus which are classified according to their cell type and projection fibers.
The general structure of the dendrite is used to classify neurons into multipolar, bipolar and unipolar types. Multipolar neurons are composed of one axon and many dendritic trees. Pyramidal cells are multipolar cortical neurons with pyramid-shaped cell bodies and large dendrites that extend towards the surface of the cortex (apical dendrite ...