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The simplest type of kidney in mammals is the unipapillary kidney, consisting of a cortex, medulla, and renal pelvis. [163] But the unipapillary kidney is limited by the number of nephrons at which it functions optimally. [20] It is assumed that unipapillary kidney was the original kidney structure in mammals, from which multilobar kidneys ...
Madin-Darby canine kidney (MDCK) cells are a model mammalian cell line used in biomedical research. MDCK cells are used for a wide variety of cell biology studies including cell polarity , cell-cell adhesions (termed adherens junctions ), collective cell motility, toxicity studies, [ 1 ] as well as responses to growth factors.
Stones can form in any part of the urinary tract in dogs and cats, but unlike in humans, stones of the kidney are less common and do not often cause significant disease, although they can contribute to pyelonephritis and chronic kidney disease. Types of stones include struvite, calcium oxalate, urate, cystine, calcium phosphate, and silicate ...
The outer layer of each kidney is made up of a fibrous sheath called the renal capsule. The peripheral layer of the kidney is called the cortex and the inner part is called the medulla. The medulla consists of one or more pyramids, the bases of which start from corticomedullary border. Medulla pyramid with overlying cortex comprises the renal ...
Diagram of the circulation related to a single glomerulus, associated tubule, and collecting system The renal corpuscle in the cortex (outer layer) of the kidney. At the top, the renal corpuscle containing the glomerulus. The filtered blood exits into the renal tubule as filtrate, at right. At left, blood flows from the afferent arteriole (red ...
The renal cortex is the outer portion of the kidney between the renal capsule and the renal medulla. [1] In the adult, it forms a continuous smooth outer zone with a number of projections ( cortical columns ) that extend down between the pyramids .
The renal pelvis is the location of several kinds of kidney cancer and is affected by infection in pyelonephritis. [citation needed] A large "staghorn" kidney stone may block all or part of the renal pelvis. The size of the renal pelvis plays a major role in the grading of hydronephrosis.
The glomerulus and its surrounding Bowman's capsule constitute a renal corpuscle, the basic filtration unit of the kidney. [2] The rate at which blood is filtered through all of the glomeruli, and thus the measure of the overall kidney function, is the glomerular filtration rate.