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The dental lamina is a band of epithelial tissue seen in histologic sections of a developing tooth. [1] [2] The dental lamina is first evidence of tooth development and begins (in humans) at the sixth week in utero or three weeks after the rupture of the buccopharyngeal membrane. It is formed when cells of the oral ectoderm proliferate faster ...
In the inductive stage, the morphodifferentiation phase the shape of the crown is determined by the bell stage of tooth development. There is a basal lamina between the IEE and the dental papilla. [6] At this time, the dentin is not mineralized. The IEE cuboidal or low columnar with centralized nuclei and poorly developed Golgi complexes.
The other dominant hypothesis, the "clone model", proposes that the epithelium programs a group of ectomesenchymal cells to generate teeth of particular shapes. This group of cells, called a clone, coaxes the dental lamina into tooth development, causing a tooth bud to form. Growth of the dental lamina continues in an area called the "progress ...
Tooth development begins at week 6 in utero, in the oral epithelium. The process is divided into three stages: Initiation; Morphogenesis and; Histogenesis [2]; At the end of week 7 i.u., localised proliferations of cells in the dental laminae form round and oval swellings known as tooth buds, which will eventually develop into mesenchymal cells and surround the enamel organ.
Also during the cap stage is the formation of a depression within the deepest part of each tooth bud of the dental lamina. The dental lamina is a band of epithelial tissue which connects the developing tooth bud to the oral epithelium. The dental lamina eventually disintegrates into small clusters of epithelium and is reabsorbed. The dental ...
This tissue is primarily basal lamina. It is usually worn away by mastication and cleaning. The primary enamel cuticle protects enamel from resorption by cells of the dental sac and also secretes desmolytic enzymes for elimination of the dental sac, allowing fusion between reduced enamel epithelium and oral epithelium.
The first sign of tooth development is known to be as early as the 6th week of intrauterine life. The oral epithelium begins to multiply and invaginates into ectomesenchyme cells, which gives rise to dental lamina. The dental lamina is the origin of the tooth bud. The bud stage progresses to the cap stage when the epithelium forms the enamel organ.
A set of human teeth under an orthopantomogram. Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.