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This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors. It includes inhibitory , excitatory , and neurotrophic neurosteroids as well as pheromones and vomeropherines .
Zuranolone, an example of a neurosteroid, used for the treatment of postpartum depression. Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.
List of neurosteroids – excitatory, inhibitory, mixed, neurotrophic, antineurotrophic, and other neurosteroids, as well as pheromones and pherines List of steroidogenesis inhibitors – steroidogenesis inhibitors , or inhibitors of steroid biosynthesis and metabolism
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Pherines, also known as vomeropherines, are odorless synthetic neuroactive steroids that engage nasal chemosensory receptors and induce dose-dependent and reversible pharmacological and behavioral effects.
Tetrahydrodeoxycorticosterone (abbreviated as THDOC; 3α,21-dihydroxy-5α-pregnan-20-one), also referred to as allotetrahydrocorticosterone, is an endogenous neurosteroid. [1]
5α-Dihydrocorticosterone (5α-DHC, 5α-DHB), also known as 11β,21-dihydroxy-5α-pregnane-3,20-dione, is a naturally occurring, endogenous glucocorticoid steroid hormone and neurosteroid. [1] [2] [3] It is biosynthesized from corticosterone by the enzyme 5α-reductase. [4] [5] [6] DHC has central depressant effects and impairs long-term ...
Alfaxalone is used as an induction agent, an injectable anesthetic, and a sedative in animals. [5] While it is commonly used in cats and dogs, it has also been successfully used in rabbits, [6] horses, sheep, pigs, and exotics such as red-eared turtles, axolotl, green iguanas, marmosets, [7] and koi fish. [8]