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This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors. It includes inhibitory , excitatory , and neurotrophic neurosteroids as well as pheromones and vomeropherines .
Zuranolone, an example of a neurosteroid, used for the treatment of postpartum depression. Neurosteroids, also known as neuroactive steroids, are endogenous or exogenous steroids that rapidly alter neuronal excitability through interaction with ligand-gated ion channels and other cell surface receptors.
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Certain drugs show weak GABA A receptor NAM activity as an off-target activity that is responsible for undesirable side effects like anxiety, insomnia, and seizures. Examples include fluoroquinolone antibiotics like ciprofloxacin , [ 10 ] β-lactam antibiotics like penicillin , ceftriaxone , and imipenem , [ 10 ] [ 11 ] nonsteroidal ...
List of neurosteroids – excitatory, inhibitory, mixed, neurotrophic, antineurotrophic, and other neurosteroids, as well as pheromones and pherines List of steroidogenesis inhibitors – steroidogenesis inhibitors , or inhibitors of steroid biosynthesis and metabolism
Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. [10] [11] As a medication, allopregnanolone is referred to as brexanolone, sold under the brand name Zulresso, [6] [12] and used to treat postpartum depression.
Tetrahydrodeoxycorticosterone (abbreviated as THDOC; 3α,21-dihydroxy-5α-pregnan-20-one), also referred to as allotetrahydrocorticosterone, is an endogenous neurosteroid. [1]
The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic. Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing. However, these classifications are based on laboratory behavior.