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The macula (/ˈmakjʊlə/) [1] or macula lutea is an oval-shaped pigmented area in the center of the retina of the human eye and in other animals. The macula in humans has a diameter of around 5.5 mm (0.22 in) and is subdivided into the umbo, foveola, foveal avascular zone, fovea, parafovea, and perifovea areas.
The fovea centralis is a small, central pit composed of closely packed cones in the eye.It is located in the center of the macula lutea of the retina. [1] [2]The fovea is responsible for sharp central vision (also called foveal vision), which is necessary in humans for activities for which visual detail is of primary importance, such as reading and driving.
Lutein and zeaxanthin act as antioxidants that protect the retina and macula from oxidative damage from high-energy light waves. [107] As the light waves enter the eye, they excite electrons that can cause harm to the cells in the eye, but they can cause oxidative damage that may lead to macular degeneration or cataracts.
The incidence of age-related macular degeneration and its associated features increases with age and is low in people <55 years of age. [101] Smoking is the strongest modifiable risk factor. [102] As of 2008, age-related macular degeneration accounts for more than 54% of all vision loss in the white population in the US. [103]
The retina (from Latin rete 'net'; pl. retinae or retinas) is the innermost, light-sensitive layer of tissue of the eye of most vertebrates and some molluscs.The optics of the eye create a focused two-dimensional image of the visual world on the retina, which then processes that image within the retina and sends nerve impulses along the optic nerve to the visual cortex to create visual perception.
Choroid dissected from a calf's eye, showing black RPE and iridescent blue tapetum lucidum. The RPE was known in the 18th and 19th centuries as the pigmentum nigrum, referring to the observation that the RPE is dark (black in many animals, brown in humans); and as the tapetum nigrum, referring to the observation that in animals with a tapetum lucidum, in the region of the tapetum lucidum the ...
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