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  2. Bi-specific T-cell engager - Wikipedia

    en.wikipedia.org/wiki/Bi-specific_T-cell_engager

    Structure of a BiTE. V H: Heavy chain variable regions. V L: Light chain variable regions. Different specificity is marked with different colours and shapes. The arrows point from N-to C-terminus. Bi-specific T-cell engager (BiTE) is a class of artificial bispecific monoclonal antibodies that are investigated for use as anti-cancer drugs.

  3. National Institute for Health and Care Excellence - Wikipedia

    en.wikipedia.org/wiki/National_Institute_for...

    Where NICE has approved a treatment, the NHS must fund it. But not all treatments have been assessed by NICE and these treatments are usually dependent on local NHS decision making. In the case of cancer the Cancer Drugs Fund was set up in 2011 after complaints about NICE decisions on new and expensive cancer drugs with limited benefits.

  4. Blinatumomab - Wikipedia

    en.wikipedia.org/wiki/Blinatumomab

    Blinatumomab linking a T cell to a malignant B cell.. Blinatumomab is a bispecific T-cell engager (BiTE). [7] It enables a patient's T cells to recognize malignant B cells. A molecule of blinatumomab combines two binding sites: a CD3 site for T cells and a CD19 site for the target B cells.

  5. Cancer prevention - Wikipedia

    en.wikipedia.org/wiki/Cancer_prevention

    Advertisement for a healthy diet to possibly reduce cancer risk. An average 35% of human cancer mortality is attributed to the diet of the individual. [9] Studies have linked excessive consumption of red or processed meat to an increased risk of breast cancer, colon cancer, and pancreatic cancer, a phenomenon which could be due to the presence of carcinogens in meats cooked at high temperatures.

  6. Haddon Matrix - Wikipedia

    en.wikipedia.org/wiki/Haddon_Matrix

    The Haddon Matrix is the most commonly used paradigm in the injury prevention field. Developed by William Haddon in 1970, the matrix looks at factors related to personal attributes, vector or agent attributes and environmental attributes; before, during and after an injury or death. By utilizing this framework, one can then think about ...

  7. List of medically significant spider bites - Wikipedia

    en.wikipedia.org/wiki/List_of_medically...

    The Australian red-back and North American widow species live near humans and bites are frequent, numbering thousands yearly. The venom produces very painful effects including muscle spasms, 'tetanus-like' contractions, nausea and vomiting, and severe generalized pain. A serious bite will often require a short hospital stay to control pain.

  8. Amgen (AMGN) Q4 2024 Earnings Call Transcript - AOL

    www.aol.com/finance/amgen-amgn-q4-2024-earnings...

    Our second approved BiTE therapy, IMDELLTRA, a first-in-class bispecific T cell engager targeting DLL3 for small cell lung cancer, is rapidly advancing into earlier lines of therapy.

  9. Skeeter syndrome - Wikipedia

    en.wikipedia.org/wiki/Skeeter_syndrome

    The Skeeter syndrome should not be confused with another type of reactivity to mosquito bites, severe mosquito bite allergy (SMBA). SMBA is most often an Epstein-Barr virus-associated lymphoproliferative disease that complicates ~33% of individuals with chronic active Epstein-Barr virus infection or, in extremely rare cases, individuals with Epstein-Barr virus-positive Hodgkin disease or an ...