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The causes of autoantibody production are varied and not well understood. It is thought that some autoantibody production is due to a genetic predisposition combined with an environmental trigger, such as a viral illness or a prolonged exposure to certain toxic chemicals. There is generally not a direct genetic link however.
The main symptoms include several kinds of skin rash along with muscle weakness in both upper arms or thighs. [8] Although dermatomyositis is closely related to polymyositis and is sometimes assumed to be a complication of that disease, most patients with dermatomyositis develop skin symptoms before any muscle involvement.
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
26 pictures of skin rashes to help you identify your skin rash. Plus, doctor-approved at-home skin rash remedies and when to see a doctor for your skin rash. ... medication, or autoimmune disease ...
Contact dermatitis. What it looks like: Contact dermatitis has the same symptoms mentioned above, and can be a red rash that appears scaly or blistered, depending on its cause and severity.This ...
Skin tests, such as the autologous serum skin test (ASST), can be used to detect the presence of functional autoantibodies. In this test, a small amount of the patient's serum is injected into the skin. A positive reaction, which is the formation of a wheal and flare, indicates the presence of functional autoantibodies. [33]
Autoantibody testing: Many autoimmune diseases are characterized by the presence of autoantibodies. Blood tests can identify these antibodies, which are directed against the body's own tissues. [66] For example, antinuclear antibody (ANA) testing is commonly used in the diagnosis of systemic lupus erythematosus and other autoimmune diseases.
Dermatomyositis: an inflammatory disease of skin and muscle marked especially by muscular weakness and skin rash. Scleroderma is a connective tissue disease that causes fibrosis and vascular abnormalities, but that also has an autoimmune component, and can include connective tissues complications.