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Lymphangiomatosis can occur at any age, but the incidence is highest in children and teenagers. Signs and symptoms are typically present before the age of 20 and the condition is often under-recognized in adults. [2] It affects males and females of all races and exhibits no inheritance pattern.
The prognosis for lymphangioma circumscriptum and cavernous lymphangioma is generally excellent. This condition is associated with minor bleeding, recurrent cellulitis , and lymph fluid leakage. Two cases of lymphangiosarcoma arising from lymphangioma circumscriptum have been reported; however, in both of the patients, the preexisting lesion ...
Gorham's disease (pronounced GOR-amz), also known as Gorham vanishing bone disease and phantom bone disease, [1] is a very rare skeletal condition of unknown cause.It is characterized by the uncontrolled proliferation of distended, thin-walled vascular or lymphatic channels within bone, which leads to resorption and replacement of bone with angiomas and/or fibrosis.
In a cohort of patients in the United Kingdom, 10 years after symptom onset, 55% of 77 patients were breathless walking on flat ground and 10% were housebound. [127] The average annual rate of decline in FEV1 and DLCO in 275 patients studied in a single pulmonary function laboratory at the NHLBI was 75 ± 9 mL, and 0.69 ± 0.07 mL/min/mm Hg ...
Given the phenotypic variability, there are no established diagnostic criteria. Instead, the diagnosis is made based on clinical evidence and supporting histopathology that demonstrates the presence of positive lymphatic markers, such as podoplanin (D2-40) or lymphatic vessel endothelial hyaluronan receptor 1 (), as well as negative glucose transporter 1 ().
Acquired progressive lymphangioma, also known as benign lymphangioendothelioma is a group of lymphangiomas that occur anywhere in young individuals, grow slowly, and present as bruise-like lesions or erythematous macules.
Treatment is often pursued for troubling symptoms (itching, pain) or for cosmetic reasons. Surgical removal (excision) of the affected skin layers is the most common and effective treatment. Ablative carbon dioxide laser therapy is a less invasive method that can improve the appearance.
Lymphangitis carcinomatosa most often affects people 40–49 years of age. [ 1 ] Lymphangitis carcinomatosa may be caused by the following malignancies as suggested by the mnemonic: " C ertain C ancers S pread B y P lugging T he L ymphatics" ( cervical cancer , colon cancer , stomach cancer , breast cancer /bronchiogenic carcinoma, pancreatic ...