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In January 2014, Bayer's CEO Marijn Dekkers allegedly stated that Nexavar was developed for "Western patients who can afford it, not for Indians". A kidney cancer patient would pay $96,000 (£58,000) for a year's course of the Bayer-made drug, whereas the cost of the Indian version of the generic drug would be around $2,800 (£1,700). [29]
The combination is also used to treat HCC patients who have been given Nexavar. Opdivo, which is one of the top sellers for Bristol Myers, brought in $9.01 billion in revenue in 2023, while Yervoy ...
Ultimately, when a drug is marketed it may be used in patient populations that were not studied during clinical trials (children, the elderly, pregnant women, patients with co-morbidities not found in the clinical trial population, etc.) and a different set of warnings, precautions or contraindications (where the drug should not be used at all ...
Contraindications - lists situations in which the medication should not be used, for example in patients with other medical conditions such as kidney problems or allergies; Warnings - covers possible serious side effects that may occur (e.g., boxed warning)
In April 2005, FDA advisors requested that Pfizer place a boxed warning on their non-steroidal anti-inflammatory drug Celebrex for cardiovascular and gastrointestinal risks. [9] [10] In 2005, the FDA issued a boxed warning regarding the risk of atypical antipsychotics being prescribed among elderly patients with dementia. This advisory was ...
The Beers Criteria for Potentially Inappropriate Medication Use in Older Adults, commonly called the Beers List, [1] are guidelines published by the American Geriatrics Society (AGS) for healthcare professionals to help improve the safety of prescribing medications for adults 65 years and older in all except palliative settings.
With reports of elderly victims of political scammers on the rise, the payment giant that transacted $481 billion in the first half of 2024 says families need to get involved.
Temozolomide, sold under the brand name Temodar among others, is an anticancer medication used to treat brain tumors such as glioblastoma and anaplastic astrocytoma. [4] [5] It is taken by mouth or via intravenous infusion.