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  2. Membrane potential - Wikipedia

    en.wikipedia.org/wiki/Membrane_potential

    The ion pump most relevant to the action potential is the sodium–potassium pump, which transports three sodium ions out of the cell and two potassium ions in. [14] [15] As a consequence, the concentration of potassium ions K + inside the neuron is roughly 30-fold larger than the outside concentration, whereas the sodium concentration outside ...

  3. Two-pore channel - Wikipedia

    en.wikipedia.org/wiki/Two-pore_channel

    The two subunit domains are separated by an EF-hand domain that has a calcium ion binding motif. This binding motif can facilitate channel activation by cytosolic calcium ions. Each of the two subunits are built from 12 transmembrane helices. The two central pore domains are combined from the voltage sensing domains, VSD1 and VSD2.

  4. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    The course of the action potential can be divided into five parts: the rising phase, the peak phase, the falling phase, the undershoot phase, and the refractory period. During the rising phase the membrane potential depolarizes (becomes more positive). The point at which depolarization stops is called the peak phase. At this stage, the membrane ...

  5. Ionophore - Wikipedia

    en.wikipedia.org/wiki/Ionophore

    The structure of the complex of sodium (Na +) and the antibiotic monensin A Structure of a potassium complex of a crown ether, a synthetic ionophore-ion complex. Biological activities of metal ion-binding compounds can be changed in response to the increment of the metal concentration, and based on the latter compounds can be classified as "metal ionophores", "metal chelators" or "metal ...

  6. Potassium in biology - Wikipedia

    en.wikipedia.org/wiki/Potassium_in_biology

    Potassium is the major cation (K +, a positive ion) inside animal cells, while sodium (Na +) is the major cation outside animal cells.The difference between the concentrations of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential.

  7. Ion channel - Wikipedia

    en.wikipedia.org/wiki/Ion_channel

    Ion channels are also classified according to their subcellular localization. The plasma membrane accounts for around 2% of the total membrane in the cell, whereas intracellular organelles contain 98% of the cell's membrane. The major intracellular compartments are endoplasmic reticulum, Golgi apparatus, and mitochondria. On the basis of ...

  8. Ion transporter - Wikipedia

    en.wikipedia.org/wiki/Ion_transporter

    Diffusion vs. Transport. In biology, an ion transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different biological functions, including cellular communication, maintaining homeostasis, energy production, etc. [1] There are different types of transporters including pumps, uniporters, antiporters, and symporters.

  9. Chemiosmosis - Wikipedia

    en.wikipedia.org/wiki/Chemiosmosis

    Chemiosmosis is the movement of ions across a semipermeable membrane bound structure, down their electrochemical gradient. An important example is the formation of adenosine triphosphate (ATP) by the movement of hydrogen ions (H +) across a membrane during cellular respiration or photosynthesis.