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From the point of view of control theory, the voltage clamp experiment can be described in terms of the application of a high-gain output feedback control law [13] to the neuronal membrane. [14] Mathematically, the membrane voltage can be modeled by a conductance-based model with an input given by the applied current I a p p ( t ...
The aqueous solution in the classical reaction contains glucose, sodium hydroxide and methylene blue. [14] In the first step an acyloin of glucose is formed. The next step is a redox reaction of the acyloin with methylene blue in which the glucose is oxidized to diketone in alkaline solution [6] and methylene blue is reduced to colorless leucomethylene blue.
The neurotransmitter most often associated with EPSPs is the amino acid glutamate, and is the main excitatory neurotransmitter in the central nervous system of vertebrates. [2]
Cell excitability is the change in membrane potential that is necessary for cellular responses in various tissues. The resting potential forms the basis of cell excitability and these processes are fundamental for the generation of graded and action potentials. Normal and pathological activities in the heart and brain can be modelled as ...
Design of Experiments: A systematic, rigorous approach to engineering problem-solving that applies principles and techniques at the data collection stage so as to ensure the generation of valid, defensible, and supportable engineering conclusions [1] Design Point: A single combination of settings for the independent variables of an experiment.
In neurons that are involved in chemical synaptic transmission, neurotransmitters are synthesized either in the neuronal cell body, or within the presynaptic terminal, depending on the type of neurotransmitter being synthesized and the location of enzymes involved in its synthesis.
It was named after Richard FitzHugh (1922–2007) [2] who suggested the system in 1961 [3] and Jinichi Nagumo et al. who created the equivalent circuit the following year. [4]In the original papers of FitzHugh, this model was called Bonhoeffer–Van der Pol oscillator (named after Karl-Friedrich Bonhoeffer and Balthasar van der Pol) because it contains the Van der Pol oscillator as a special ...
An experiment is a procedure carried out to support or refute a hypothesis, or determine the efficacy or likelihood of something previously untried. Experiments provide insight into cause-and-effect by demonstrating what outcome occurs when a particular factor is manipulated.