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Docusate is the common chemical and pharmaceutical name of the anion bis(2-ethylhexyl) sulfosuccinate, also commonly called dioctyl sulfosuccinate (DOSS). [2] [3] [4]Salts of this anion, especially docusate sodium, are widely used in medicine as an emollient laxative and as stool softeners, by mouth or rectally. [1]
Compounds that prolong the action potential: matching the modern classification, with the key drug example being amiodarone, and a surgical example being thyroidectomy. This was not a defining characteristic in an earlier review by Charlier et al. (1968), [17] but was supported by experimental data presented by Vaughan Williams (1970).
Effect of class III antiarrhythmic agent on cardiac action potential. Potassium channel blockers used in the treatment of cardiac arrhythmia are classified as class III antiarrhythmic agents. Atrial cardiomyocytes contain a specific subset of potassium ion channels which are absent in the ventricles. [ 1 ]
Onset of action: 12–72 hours (oral), 0.25–1 hour (rectal) Examples: glycerin suppositories (Hallens), sorbitol , lactulose , and polyethylene glycol ( PEG - Colyte, MiraLax) [ 12 ] Lactulose works by the osmotic effect, which retains water in the colon; lowering the pH through bacterial fermentation to lactic, formic, and acetic acids; and ...
An action potential occurs when the membrane potential of a specific cell rapidly rises and falls. [1] This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of excitable cells, which include animal cells like neurons and muscle cells, as well as some plant cells.
A drug class is a group of medications and other compounds that share similar chemical structures, act through the same mechanism of action (i.e., binding to the same biological target), have similar modes of action, and/or are used to treat similar diseases. [1] [2] The FDA has long worked to classify and license new medications.
action potential alkaline phosphatase angina pectoris anteroposterior apical area postrema: A&P: auscultation and percussion anatomy and physiology: A/P: anatomy and physiology assessment and plan: APACHE II: Acute Physiology and Chronic Health Evaluation II: APAP: paracetamol (aka acetaminophen) (from its chemical name, N-acetyl-para-aminophenol)
The formal potential is thus the reversible potential of an electrode at equilibrium immersed in a solution where reactants and products are at unit concentration. [4] If any small incremental change of potential causes a change in the direction of the reaction, i.e. from reduction to oxidation or vice versa , the system is close to equilibrium ...