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Alzheimer's disease (AD) is a neurodegenerative disease and the most common cause of dementia; it usually occurs in old age. Familial Alzheimer's disease (FAD or EOFAD for early onset) is an inherited and uncommon form of AD. Familial AD usually strikes earlier in life, defined as before the age of 65.
It is one of the most common causes of disability among the elderly but can develop before the age of 65 when it is known as early-onset dementia or presenile dementia. [ 279 ] [ 280 ] Less than 1% of those with Alzheimer's have gene mutations that cause a much earlier development of the disease, around the age of 45, known as early-onset ...
Compared to late onset dementia, patients with early onset dementia are more likely to have dementias other than Alzheimer's disease, although Alzheimer's is the most common etiology in either case. [13] In general, early onset dementia has a faster progression and features more extensive neurological damage when compared to late onset dementia.
Pre-dementia or early-stage dementia (stages 1, 2, and 3). In this initial phase, a person can still live independently and may not exhibit obvious memory loss or have any difficulty completing ...
Mild cognitive impairment (MCI) may be caused due to alteration in the brain triggered during early stages of Alzheimer's disease, to other causes, or to a combination of causes. [14] [15] Brain damage, brain injury, delirium and prolonged substance abuse can cause MCI. HIV-associated neurocognitive disorder can cause MCI. Risk factors of both ...
It is known that patients with Alzheimer's disease and patients with semantic dementia both exhibit difficulty in tasks that involve picture naming and category fluency. This is tied to damage to their semantic network, which stores knowledge of meanings and understandings. [citation needed]
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