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  2. Noonan syndrome - Wikipedia

    en.wikipedia.org/wiki/Noonan_syndrome

    Noonan syndrome (NS) is a genetic disorder that may present with mildly unusual facial features, short height, congenital heart disease, bleeding problems, and skeletal malformations. [1]

  3. Noonan syndrome with multiple lentigines - Wikipedia

    en.wikipedia.org/wiki/Noonan_syndrome_with...

    Noonan syndrome with multiple lentigines (NSML) which is part of a group called Ras/MAPK pathway syndromes, [2] is a rare autosomal dominant, [3] multisystem disease caused by a mutation in the protein tyrosine phosphatase, non-receptor type 11 gene . The disease is a complex of features, mostly involving the skin, skeletal and cardiovascular ...

  4. Neurofibromatosis type I - Wikipedia

    en.wikipedia.org/wiki/Neurofibromatosis_type_I

    Café au lait spot characteristic of NF1 Diagnostic criteria of neurofibromatosis type I, requiring at least 2 of the mentioned items. [6]The following is a list of conditions and complications associated with NF-1, and, where available, age range of onset and progressive development, occurrence percentage of NF-1 population, method of earliest diagnosis, and treatments and related medical ...

  5. RASopathy - Wikipedia

    en.wikipedia.org/wiki/RASopathy

    Legius syndrome, also known as NF1-like syndrome; Noonan syndrome with multiple lentigines (NSML), formerly called LEOPARD syndrome; SYNGAP1-related intellectual disability; Somatic mutations in the Ras/MAPK pathway can cause cancers and disorders such as RAS-associated autoimmune leukoproliferative disorder (RALD) or juvenile myelomonocytic ...

  6. Multiple epiphyseal dysplasia - Wikipedia

    en.wikipedia.org/wiki/Multiple_epiphyseal_dysplasia

    Multiple epiphyseal dysplasia (MED) encompasses a spectrum of skeletal disorders, in which are inherited in an autosomal dominant form. However, there is an autosomal recessive form. [4] Associated genes include COL9A1, [5] COL9A2, [6] COL9A3, [7] COMP, [8] and MATN3. [9] Types include:

  7. Extrapyramidal symptoms - Wikipedia

    en.wikipedia.org/wiki/Extrapyramidal_symptoms

    Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.

  8. Medical genetics - Wikipedia

    en.wikipedia.org/wiki/Medical_genetics

    Medical genetics is the branch of medicine that involves the diagnosis and management of hereditary disorders.Medical genetics differs from human genetics in that human genetics is a field of scientific research that may or may not apply to medicine, while medical genetics refers to the application of genetics to medical care.

  9. Pseudopseudohypoparathyroidism - Wikipedia

    en.wikipedia.org/wiki/Pseudopseudohypoparathyroidism

    Treatments to reduce symptoms, genetic counseling Pseudopseudohypoparathyroidism ( PPHP ) is an inherited disorder, [ 1 ] named for its similarity to pseudohypoparathyroidism in presentation. It is more properly Albright hereditary osteodystrophy , although without resistance of parathyroid hormone (PTH), as frequently seen in that affliction.