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Basaloid squamous cell carcinoma (Bas-SqCC) is an uncommon histological variant of lung cancer composed of cells exhibiting cytological and tissue architectural features of both squamous cell lung carcinoma and basal cell carcinoma.
Basal-cell carcinoma (BCC), also known as basal-cell cancer, basalioma [7] or rodent ulcer, [8] is the most common type of skin cancer. [2] It often appears as a painless raised area of skin, which may be shiny with small blood vessels running over it. [1]
Skin cancer; A basal-cell skin cancer.Note the pearly appearance and telangiectasia.: Specialty: Oncology and dermatology: Symptoms: Basal-cell: painless raised area of skin that may be shiny with small blood vessel running over it or ulceration [1]
A microscopic image of a prostate gland featuring an example of basal cells. A basal cell is a general cell type that is present in many forms of epithelial tissue throughout the body.
Basaloid forms of lung carcinoma were first described in the peer-reviewed medical literature by Dr. Elisabeth Brambilla and her colleagues in 1992. [11] They were first recognized as distinct clinicopathological variants of both squamous cell and large cell lung cancers in 1999, within the third revision of the World Health Organization lung tumor typing and classification scheme.
basaloid squamous-cell carcinoma is mostly found in or near the tongue, tonsils, or larynx, but may also occur in the lung or elsewhere. [ 26 ] clear-cell squamous-cell carcinoma (also known as clear-cell carcinoma of the skin) is characterized by keratinocytes that appear clear as a result of hydropic swelling .
The primary function of keratinocytes is the formation of a barrier against environmental damage by heat, UV radiation, dehydration, pathogenic bacteria, fungi, parasites, and viruses.
Classic vulvar intraepithelial neoplasia: associated with developing into the warty and basaloid type carcinoma. This is associated with carcinogenic genotypes of HPV and/or HPV persistence factors such as cigarette smoking or immunocompromised states.