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Water intoxication can be prevented if a person's intake of water does not grossly exceed their losses. Healthy kidneys can excrete approximately 800 millilitres to one litre of fluid water (0.84–1.04 quarts) per hour. [15] However, stress (from prolonged physical exertion), as well as disease states, can greatly reduce this amount. [15]
The symptoms of dehydration become increasingly severe with greater total body water loss. A body water loss of 1-2%, considered mild dehydration, is shown to impair cognitive performance. [ 8 ] While in people over age 50, the body's thirst sensation diminishes with age, a study found that there was no difference in fluid intake between young ...
The kidneys may be affected, resulting in blood or protein in the urine, and acute kidney failure. People can have decreased urine production, fluid retention, and confusion. [citation needed] Other signs and symptoms can include: [4] Chest pain; Abnormal heart rhythms; Headache; Nosebleeds that are difficult to stop; Dyspnea
“When the kidneys shut down, it would be difficult to also regulate your blood pressure so many [people] with nephrotic syndrome and kidney disease have high blood pressure challenges to also ...
Granulomatosis with polyangiitis 50-60% have ophthalmologic manifestations, which can be a presenting feature in a minority of patients. Orbital disease is the most common manifestation, and may result in proptosis , restrictive ophthalmopathy , chronic orbital pain, and in chronic cases, orbital retraction syndrome and intractable socket pain.
The kidneys can also generate dilute urine to balance sodium levels. [8] These electrolytes must be replaced to keep the electrolyte concentrations of the body fluids constant. Hyponatremia, or low sodium, is the most commonly seen type of electrolyte imbalance.