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  2. Stratum spinosum - Wikipedia

    en.wikipedia.org/wiki/Stratum_spinosum

    Keratinization begins in the stratum spinosum, [5] although the actual keratinocytes begin in the stratum basale. [4] They have large pale-staining nuclei as they are active in synthesizing fibrillar proteins, known as cytokeratin , which build up within the cells aggregating together forming tonofibrils .

  3. Keratin - Wikipedia

    en.wikipedia.org/wiki/Keratin

    Microscopy of keratin filaments inside cells. Keratin (/ ˈ k ɛr ə t ɪ n / [1] [2]) is one of a family of structural fibrous proteins also known as scleroproteins.It is the key structural material making up scales, hair, nails, feathers, horns, claws, hooves, and the outer layer of skin in vertebrates.

  4. Keratohyalin - Wikipedia

    en.wikipedia.org/wiki/Keratohyalin

    Keratohyalin is a protein structure found in cytoplasmic granules of the keratinocytes in the stratum granulosum of the epidermis.Keratohyalin granules (KHG) mainly consist of keratin, profilaggrin, [1] loricrin [2] and trichohyalin proteins which contribute to cornification or keratinization, the process of the formation of epidermal cornified cell envelope.

  5. Keratinocyte - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte

    Keratinization is part of the physical barrier formation (cornification), in which the keratinocytes produce more and more keratin and undergo terminal differentiation. The fully cornified keratinocytes that form the outermost layer are constantly shed off and replaced by new cells.

  6. Cytokeratin - Wikipedia

    en.wikipedia.org/wiki/Cytokeratin

    Keratin intermediate filaments in epithelial cells (red stain). Cytokeratins are keratin proteins found in the intracytoplasmic cytoskeleton of epithelial tissue.They are an important component of intermediate filaments, which help cells resist mechanical stress. [1]

  7. Oral mucosa - Wikipedia

    en.wikipedia.org/wiki/Oral_mucosa

    Keratinization is the differentiation of keratinocytes in the stratum granulosum into nonvital surface cells or squames to form the stratum corneum. The cells terminally differentiate as they migrate to the surface from the stratum basale where the progenitor cells are located to the superficial surface.

  8. Lamellar bodies - Wikipedia

    en.wikipedia.org/wiki/Lamellar_bodies

    Red arrows indicate secreted lamellar bodies, and green arrows indicate lamellar bodies in the cytoplasm. Scale bar = 200 nm. In cell biology, lamellar bodies (otherwise known as lamellar granules, membrane-coating granules (MCGs), keratinosomes or Odland bodies) are secretory organelles found in type II alveolar cells in the lungs, and in keratinocytes in the skin.

  9. Keratin 1 - Wikipedia

    en.wikipedia.org/wiki/Keratin_1

    16678 Ensembl ENSG00000167768 ENSMUSG00000046834 UniProt P04264 P04104 RefSeq (mRNA) NM_006121 NM_008473 RefSeq (protein) NP_006112 NP_032499 Location (UCSC) Chr 12: 52.67 – 52.68 Mb Chr 15: 101.75 – 101.76 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Keratin 1 is a Type II intermediate filament (IFs) of the intracytoplasmatic cytoskeleton. Is co-expressed with and binds to ...